Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30279190 | 1.00 | KMT2A (0.51) | KMT2AMEN1KDM4EALDH1A1MAPT | |
| SCHEMBL30874370 | 0.81 | KDM4E (0.47) | KMT2AMEN1KDM4EALDH1A1MAPT | |
| SCHEMBL18956056 | 0.81 | KDM4E (0.47) | KMT2AMEN1KDM4EALDH1A1MAPT | |
| SCHEMBL30279202 | 0.79 | KMT2A (0.42) | KMT2AMEN1KDM4EALDH1A1MAPT | |
| SCHEMBL25073869 | 0.79 | KMT2A (0.42) | KMT2AMEN1KDM4EALDH1A1MAPT | |
| SCHEMBL30279167 | 0.78 | KDM4E (0.45) | KMT2AMEN1KDM4EALDH1A1MAPT | |
| SCHEMBL25073774 | 0.78 | KDM4E (0.45) | KMT2AMEN1KDM4EALDH1A1MAPT | |
| SCHEMBL30279166 | 0.78 | KDM4E (0.45) | KMT2AMEN1KDM4EALDH1A1MAPT | |
| SCHEMBL4591466 | 0.77 | KMT2A (0.49) | KMT2AMEN1KDM4EALDH1A1MAPT | |
| SCHEMBL25073875 | 0.76 | PSMB1 (0.44) | KDM4EPSMB1PSMB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023021278-A1 | PHENYL- AND PYRIDOPYRAZOLE DERIVATIVES AS INHIBITORS OF DDR1 | REDX PHARMA PLC (GB) | 2023-02-23 | — | — | WO | disclosed |