Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 6/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.46 |
| ▸ | PGR | P06401 | 3/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.43 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | RORA | P35398 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9816601 | 0.87 | PGR (0.39) | PGRNR1H2F2PRSS1PRSS2 | |
| SCHEMBL5401910 | 0.82 | CA1 (0.43) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL1683275 | 0.80 | F2 (0.54) | CA12CA1CA2CA9GAA | |
| SCHEMBL6541927 | 0.78 | KMT2A (0.46) | ALDH1A1 | |
| SCHEMBL31408776 | 0.78 | F2 (0.57) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL10515303 | 0.78 | DDB1 (0.34) | — | |
| SCHEMBL6654348 | 0.78 | CA1 (0.39) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL10829353 | 0.78 | LMNA (0.44) | CA1CA2GAAALDH1A1F2 | |
| SCHEMBL7869254 | 0.77 | F2 (0.35) | F2PRSS1PRSS2PRSS3 | |
| SCHEMBL11702088 | 0.77 | DDB1 (0.31) | F2PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023023664-A1 | SULFONYL-TRIAZOLES USEFUL AS COVALENT KINASE LIGANDS | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2023-02-23 | — | — | WO | disclosed |
| WO-2023023376-A2 | SULFONYL-TRIAZOLES USEFUL AS COVALENT KINASE LIGANDS | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2023-02-23 | — | — | WO | disclosed |