Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 9/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CTSG | P08311 | 1/20 | 0.36 |
| ▸ | CMA1 | P23946 | 1/20 | 0.36 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.34 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25074811 | 0.87 | NFE2L2 (0.46) | PGRNR1H2F2PRSS1PRSS2 | |
| SCHEMBL5401910 | 0.85 | CA1 (0.43) | TDP1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL6654348 | 0.80 | CA1 (0.39) | F2PRSS1PRSS2PRSS3MEN1 | |
| SCHEMBL10829353 | 0.80 | LMNA (0.44) | HTTF2PRSS1PRSS2PRSS3 | |
| SCHEMBL11702088 | 0.79 | DDB1 (0.31) | F2PRSS1PRSS2PRSS3 | |
| SCHEMBL26812 | 0.78 | HTT (0.47) | HTTSOS1F2PRSS1PRSS2 | |
| SCHEMBL10515303 | 0.77 | DDB1 (0.34) | — | |
| SCHEMBL11593746 | 0.77 | NFE2L2 (0.41) | PGRKAT6A | |
| SCHEMBL31408776 | 0.77 | F2 (0.57) | TDP1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL6541927 | 0.77 | KMT2A (0.46) | L3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0133657-B1 | THERMOPLASTIC COMPOSITION AND PROCESS | GENERAL ELECTRIC COMPANY (US) | 1991-10-23 | — | — | EP | claimed |
| US-4579905-A | USING MULTIFUNCTIONAL GRAFT LINKING AGENT | GENERAL ELECTRIC COMPANY (US) | 1986-04-01 | — | — | US | claimed |
| EP-0133657-B1 | THERMOPLASTIC COMPOSITION AND PROCESS | GENERAL ELECTRIC COMPANY (US) | 1991-10-23 | — | — | EP | disclosed |
| US-4579905-A | USING MULTIFUNCTIONAL GRAFT LINKING AGENT | GENERAL ELECTRIC COMPANY (US) | 1986-04-01 | — | — | US | disclosed |
| EP-0133657-A2 | Thermoplastic composition and process | GENERAL ELECTRIC COMPANY (US) | 1985-03-06 | — | — | EP | disclosed |