Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 5/20 | 0.44 |
| ▸ | ZAP70 | P43403 | 3/20 | 0.44 |
| ▸ | CAMK1D | Q8IU85 | 1/20 | 0.44 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.43 |
| ▸ | BTK | Q06187 | 1/20 | 0.43 |
| ▸ | ITK | Q08881 | 1/20 | 0.43 |
| ▸ | BCDIN3D | Q7Z5W3 | 3/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | CDK1 | P06493 | 2/20 | 0.37 |
| ▸ | PRKCA | P17252 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | VNN1 | O95497 | 1/20 | 0.35 |
| ▸ | STK17A | Q9UEE5 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23025737 | 0.81 | HDAC3 (0.38) | HDAC3HDAC1HDAC2HDAC6RXRA | |
| SCHEMBL24584789 | 0.78 | FERMT2 (0.40) | SYKZAP70BCDIN3DCDK1ALDH1A1 | |
| SCHEMBL15424474 | 0.77 | ULK1 (0.41) | HDAC3HDAC1HDAC2HDAC6ALDH1A1 | |
| SCHEMBL5093662 | 0.77 | RAB9A (0.54) | ALDH1A1 | |
| SCHEMBL21446944 | 0.76 | LCK (0.41) | BTKHDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL24655829 | 0.75 | SYK (0.41) | SYKZAP70CAMK1DPRKCEBTK | |
| SCHEMBL18881735 | 0.74 | AOC3 (0.41) | HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL19447774 | 0.74 | AOC3 (0.41) | HDAC3HDAC1HDAC2HDAC6RXRA | |
| SCHEMBL9988637 | 0.74 | NPC1 (0.43) | SYKZAP70HDAC3HDAC1HDAC2 | |
| SCHEMBL25075278 | 0.74 | SYK (0.46) | SYKZAP70RXRAGRIN1GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023020479-A1 | PARP7 INHIBITOR AND APPLICATION THEREOF | 重庆华森制药股份有限公司 | 2023-02-23 | — | — | WO | disclosed |