Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR3 | P49682 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 6/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 6/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 6/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.37 |
| ▸ | TIPARP | Q7Z3E1 | 1/20 | 0.37 |
| ▸ | LCAT | P04180 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25075358 | 0.78 | LCAT (0.41) | CXCR3CHRM4GPR119CHRM2CHRM1 | |
| SCHEMBL29208723 | 0.73 | SMN1; SMN2 (0.44) | GPR119TIPARP | |
| SCHEMBL14314163 | 0.72 | TLR7 (0.45) | CHRM4CHRM2CHRM1CHRM3 | |
| SCHEMBL24968333 | 0.71 | OGA (0.46) | CXCR3TIPARPLCAT | |
| SCHEMBL23341097 | 0.70 | OGA (0.45) | — | |
| SCHEMBL23341085 | 0.69 | IDH2 (0.52) | — | |
| SCHEMBL23341096 | 0.69 | IDH2 (0.52) | — | |
| SCHEMBL25899065 | 0.68 | GPR119 (0.41) | CXCR3GPR119LCAT | |
| SCHEMBL29729367 | 0.67 | EIF2AK4 (0.57) | — | |
| SCHEMBL25075257 | 0.66 | AOC3 (0.44) | TIPARPLCAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023020479-A1 | PARP7 INHIBITOR AND APPLICATION THEREOF | 重庆华森制药股份有限公司 | 2023-02-23 | — | — | WO | disclosed |