Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.46 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8121938 | 0.83 | ALDH1A1 (0.60) | ALDH1A1MAPTL3MBTL1LMNAGAA | |
| SCHEMBL31032981 | 0.81 | KDM4E (0.66) | ALDH1A1MAPTL3MBTL1LMNAGAA | |
| SCHEMBL10004025 | 0.80 | ALDH1A1 (0.57) | ALDH1A1MAPTL3MBTL1LMNAGAA | |
| SCHEMBL18061496 | 0.78 | ALDH1A1 (0.54) | ALDH1A1MAPTL3MBTL1LMNAGAA | |
| SCHEMBL10748352 | 0.78 | ALDH1A1 (0.58) | ALDH1A1MAPTL3MBTL1LMNAGAA | |
| SCHEMBL4675224 | 0.77 | ALOX15 (0.53) | ALDH1A1MAPTL3MBTL1LMNAGAA | |
| SCHEMBL4899931 | 0.77 | ALDH1A1 (0.50) | ALDH1A1MAPTL3MBTL1LMNAGAA | |
| SCHEMBL18395324 | 0.77 | TSHR (0.50) | ALDH1A1MAPTL3MBTL1LMNAGAA | |
| SCHEMBL6375741 | 0.76 | L3MBTL1 (0.53) | ALDH1A1MAPTL3MBTL1LMNAGAA | |
| SCHEMBL11372443 | 0.75 | ALDH1A1 (0.51) | ALDH1A1MAPTL3MBTL1LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117377665-A | PARP7 inhibitor and application thereof | 北京华森英诺生物科技有限公司 | 2024-01-09 | — | — | CN | disclosed |
| WO-2023020479-A1 | PARP7 INHIBITOR AND APPLICATION THEREOF | 重庆华森制药股份有限公司 | 2023-02-23 | — | — | WO | disclosed |