Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | GLA | P06280 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | BRD2 | P25440 | 1/20 | 0.39 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.39 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29168930 | 0.86 | TSHR (0.50) | TSHRKDM4EALDH1A1HPGDGAA | |
| SCHEMBL25075372 | 0.86 | TSHR (0.50) | TSHRKDM4EALDH1A1HPGDGAA | |
| SCHEMBL29169168 | 0.85 | TSHR (0.43) | TSHRKDM4EALDH1A1HPGDGAA | |
| SCHEMBL29169165 | 0.85 | TSHR (0.43) | TSHRKDM4EALDH1A1HPGDGAA | |
| SCHEMBL25075373 | 0.80 | TSHR (0.43) | TSHRKDM4EALDH1A1HPGDGAA | |
| SCHEMBL29169172 | 0.80 | TSHR (0.43) | TSHRKDM4EALDH1A1HPGDGAA | |
| SCHEMBL11639000 | 0.78 | ALDH1A1 (0.54) | TSHRKDM4EALDH1A1HPGDGAA | |
| SCHEMBL20594715 | 0.76 | TSHR (0.54) | TSHRKDM4EALDH1A1HPGDGAA | |
| SCHEMBL4993201 | 0.75 | TP53 (0.53) | TSHRKDM4EALDH1A1HPGDGAA | |
| SCHEMBL19787912 | 0.75 | MAPT (0.54) | TSHRKDM4EALDH1A1HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023020479-A1 | PARP7 INHIBITOR AND APPLICATION THEREOF | 重庆华森制药股份有限公司 | 2023-02-23 | — | — | WO | disclosed |