Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NOS3 | P29474 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 1/20 | 0.35 |
| ▸ | NOS2 | P35228 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4382387 | 0.91 | DPP4 (0.39) | DPP4CYP1A2MAPK1NOS3NOS1 | |
| SCHEMBL4371656 | 0.90 | ADH1C (0.38) | DPP4CYP1A2MAPK1NOS3NOS1 | |
| SCHEMBL13409415 | 0.78 | NOS3 (0.33) | DPP4NOS3NOS1NOS2 | |
| SCHEMBL10778125 | 0.77 | SLC6A2 (0.31) | — | |
| SCHEMBL12744952 | 0.70 | — | — | |
| SCHEMBL6962113 | 0.69 | — | — | |
| SCHEMBL737309 | 0.69 | — | — | |
| SCHEMBL15086891 | 0.69 | — | — | |
| SCHEMBL25163007 | 0.69 | PIK3CD (0.40) | — | |
| SCHEMBL7447366 | 0.68 | ADH1C (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023020518-A1 | N-CYCLOPROPYLPYRIDO [4, 3-D] PYRIMIDIN-4-AMINE DERIVATIVES AND USES THEREOF | JACOBIO PHARMACEUTICALS CO., LTD. (CN) | 2023-02-23 | — | — | WO | disclosed |