Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1C | P00326 | 2/20 | 0.38 |
| ▸ | ADH1A | P07327 | 2/20 | 0.38 |
| ▸ | ADH1B | P00325 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 3/20 | 0.33 |
| ▸ | CCKBR | P32239 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10778125 | 0.90 | SLC6A2 (0.31) | — | |
| SCHEMBL4371656 | 0.80 | ADH1C (0.38) | ADH1CADH1AADH1B | |
| SCHEMBL4382387 | 0.78 | DPP4 (0.39) | ADH1CADH1AADH1B | |
| SCHEMBL13301673 | 0.76 | ADH1A (0.45) | ADH1CADH1AADH1B | |
| SCHEMBL27861354 | 0.75 | ACHE (0.30) | ACHE | |
| SCHEMBL13503176 | 0.74 | ADH1A (0.43) | ADH1CADH1AADH1B | |
| SCHEMBL4570869 | 0.74 | ADH1A (0.43) | ADH1CADH1AADH1B | |
| SCHEMBL736379 | 0.72 | ADH1A (0.42) | ADH1CADH1AADH1B | |
| SCHEMBL4973138 | 0.72 | HRH4 (0.41) | ADH1CADH1A | |
| SCHEMBL10433622 | 0.72 | ADH1A (0.42) | ADH1CADH1AADH1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6482986-B1 | Benzene derivatives, preparation method and pharmaceutical compositions containing same | SANOFI-SYNTHELABO (FR) | 2002-11-19 | — | — | US | disclosed |
| EP-1192122-A1 | BENZENE DERIVATIVES, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SANOFI-SYNTHELABO (FR) | 2002-04-03 | — | — | EP | disclosed |
| WO-2000076953-A1 | BENZENE DERIVATIVES, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SANOFI-SYNTHELABO (FR) | 2000-12-21 | — | — | WO | disclosed |