Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.39 |
| ▸ | PLG | P00747 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | CTSC | P53634 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25075404 | 0.75 | SLC6A4 (0.45) | GBA1PLG | |
| SCHEMBL2241250 | 0.72 | GBA1 (0.66) | GBA1MAOAMAOB | |
| SCHEMBL18892752 | 0.71 | ARG1 (0.43) | PLG | |
| SCHEMBL10360250 | 0.71 | MAOA (0.46) | MAOAMAOBCTSLCTSBCTSS | |
| SCHEMBL10360252 | 0.71 | MAOA (0.46) | MAOAMAOBCTSLCTSBCTSS | |
| Hydrochloric Acid SCHEMBL1532936 | 0.71 | GBA1 (0.63) | GBA1MAOAMAOB | |
| SCHEMBL3044569 | 0.69 | GBA1 (0.56) | GBA1MAOB | |
| SCHEMBL1609623 | 0.69 | MAOA (0.58) | MAOAMAOBCTSLCTSBCTSS | |
| SCHEMBL13653938 | 0.69 | MAOA (0.44) | MAOAMAOBCTSLCTSBCTSS | |
| SCHEMBL20730950 | 0.69 | SLC18A3 (0.41) | GBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023023287-A1 | NOVEL HETEROCYCLIC COMPOUNDS AS SEROTONIN (5-HT) 5-HT2A AND 5-HT2C RECEPTOR POSITIVE ALLOSTERIC MODULATORS | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2023-02-23 | — | — | WO | disclosed |