Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 2/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | PLG | P00747 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GBA1 | P04062 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1502363 | 0.76 | POLB (0.55) | SLC6A4PLGPOLBGBA1 | |
| SCHEMBL18892752 | 0.75 | ARG1 (0.43) | PLG | |
| SCHEMBL25075555 | 0.75 | GBA1 (0.39) | PLGGBA1 | |
| SCHEMBL9820752 | 0.73 | PLG (0.40) | SLC6A4SLC6A2SLC6A3PLG | |
| SCHEMBL2241250 | 0.73 | GBA1 (0.66) | SLC6A4GBA1 | |
| SCHEMBL25992610 | 0.73 | SLC6A2 (0.56) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL18995298 | 0.72 | CCR3 (0.42) | SLC6A4SLC6A2SLC6A3PLG | |
| SCHEMBL9820857 | 0.72 | CCR3 (0.41) | SLC6A4SLC6A2SLC6A3PLG | |
| SCHEMBL27666282 | 0.72 | GBA1 (0.59) | SLC6A4SLC6A2SLC6A3PLGPOLB | |
| SCHEMBL16587884 | 0.72 | HRH4 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023023287-A1 | NOVEL HETEROCYCLIC COMPOUNDS AS SEROTONIN (5-HT) 5-HT2A AND 5-HT2C RECEPTOR POSITIVE ALLOSTERIC MODULATORS | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2023-02-23 | — | — | WO | disclosed |