Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 2/20 | 0.55 |
| ▸ | THRB | P10828 | 2/20 | 0.55 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.55 |
| ▸ | BCHE | P06276 | 6/20 | 0.53 |
| ▸ | ACHE | P22303 | 5/20 | 0.53 |
| ▸ | CES2 | O00748 | 1/20 | 0.51 |
| ▸ | CES1 | P23141 | 1/20 | 0.51 |
| ▸ | ESR1 | P03372 | 1/20 | 0.51 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.51 |
| ▸ | EBP | Q15125 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | SCN1A | P35498 | 1/20 | 0.49 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.49 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1283683 | 0.86 | THRB (0.69) | THRATHRBHRH3BCHEACHE | |
| SCHEMBL15052502 | 0.83 | THRA (0.58) | THRATHRBHRH3BCHEACHE | |
| SCHEMBL1283830 | 0.82 | THRA (0.71) | THRATHRBHRH3BCHEACHE | |
| SCHEMBL1283638 | 0.82 | THRA (0.67) | THRATHRBHRH3BCHEACHE | |
| SCHEMBL11224024 | 0.80 | THRA (0.77) | THRATHRBHRH3ACHEESR1 | |
| SCHEMBL5418369 | 0.80 | TP53 (0.64) | HRH3BCHEACHEEBPSIGMAR1 | |
| SCHEMBL491797 | 0.80 | L3MBTL1 (0.69) | HRH3BCHEACHEEBPSIGMAR1 | |
| SCHEMBL5424873 | 0.79 | HRH3 (0.61) | HRH3BCHEACHEESR1EBP | |
| SCHEMBL492102 | 0.79 | HRH3 (0.61) | THRATHRBHRH3BCHEACHE | |
| Hydrochloric Acid SCHEMBL11673412 | 0.77 | HRH3 (0.60) | HRH3BCHEACHEESR1EBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1482931-B1 | MONO- AND BICYCLIC AZOLE DERIVATIVES THAT INHIBIT THE INTERACTION OF LIGANDS WITH RAGE | TRANSTECH PHARMA INC (US) | 2011-10-19 | — | — | EP | disclosed |