Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.75 |
| ▸ | PPARG | P37231 | 5/20 | 0.64 |
| ▸ | PPARD | Q03181 | 5/20 | 0.64 |
| ▸ | PPARA | Q07869 | 5/20 | 0.64 |
| ▸ | F7 | P08709 | 5/20 | 0.64 |
| ▸ | F3 | P13726 | 5/20 | 0.64 |
| ▸ | TERT | O14746 | 3/20 | 0.64 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.64 |
| ▸ | FABP4 | P15090 | 3/20 | 0.64 |
| ▸ | BLM | P54132 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.64 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.64 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.64 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.64 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.64 |
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.64 |
| ▸ | PTPN7 | P35236 | 2/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15287028 | 1.00 | MAPT (0.75) | MAPTPPARGPPARDPPARAF7 | |
| SCHEMBL15808604 | 1.00 | MAPT (0.75) | MAPTPPARGPPARDPPARAF7 | |
| SCHEMBL1593964 | 1.00 | MAPT (0.75) | MAPTPPARGPPARDPPARAF7 | |
| SCHEMBL3679458 | 1.00 | MAPT (0.75) | MAPTPPARGPPARDPPARAF7 | |
| SCHEMBL2228907 | 1.00 | MAPT (0.75) | MAPTPPARGPPARDPPARAF7 | |
| SCHEMBL2566928 | 1.00 | MAPT (0.75) | MAPTPPARGPPARDPPARAF7 | |
| SCHEMBL3507735 | 1.00 | MAPT (0.75) | MAPTPPARGPPARDPPARAF7 | |
| SCHEMBL55116 | 1.00 | MAPT (0.75) | MAPTPPARGPPARDPPARAF7 | |
| SCHEMBL2228910 | 1.00 | MAPT (0.75) | MAPTPPARGPPARDPPARAF7 | |
| SCHEMBL267874 | 1.00 | MAPT (0.75) | MAPTPPARGPPARDPPARAF7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116712444-A | Active ingredient group for treating UC and key target combination thereof | 中药创新研发中心有限公司 | 2023-09-08 | — | — | CN | disclosed |
| US-20200200775-A1 | OXIDIZED LIPIDS AS BIOMARKERS FOR NEUROPATHIC PAIN | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) | 2020-06-25 | — | — | US | disclosed |
| US-10100317-B2 | Compositions of matter that reduce pain, shock, and inflammation by blocking linoleic acid metabolites and uses thereof | BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2018-10-16 | — | — | US | disclosed |
| US-20170204415-A1 | Compositions of Matter that Reduce Pain, Shock, and Inflammation by Blocking Linoleic Acid Metabolites and Uses Thereof | UNIV TEXAS (US) | 2017-07-20 | — | — | US | disclosed |
| US-9592301-B2 | Compositions of matter that reduce pain, shock, and inflammation by blocking linoleic acid metabolites and uses thereof | UNIV TEXAS (US) | 2017-03-14 | — | — | US | disclosed |
| US-20160045610-A1 | COMPOSITIONS OF MATTER THAT REDUCE PAIN, SHOCK, AND INFLAMMATION BY BLOCKING LINOLEIC ACID METABOLITES AND USES THEREOF | UNIV TEXAS (US) | 2016-02-18 | — | — | US | disclosed |
| US-9029342-B2 | Compositions of matter that reduce pain, shock, and inflammation by blocking linoleic acid metabolites and uses thereof | BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2015-05-12 | — | — | US | disclosed |
| US-20140309186-A1 | Metabolomics-Based Identification of Disease-Causing Agents | GEORGIA TECH RESEARCH CORPORATION | 2014-10-16 | — | — | US | disclosed |
| US-20140128588-A1 | COMPOSITIONS OF MATTER THAT REDUCE PAIN, SHOCK, AND INFLAMMATION BY BLOCKING LINOLEIC ACID METABOLITES AND USES THEREOF | BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2014-05-08 | — | — | US | disclosed |
| US-20110246081-A1 | Metabolomics-Based Identification of Disease-Causing Agents | GEORGIA TECH RESEARCH CORPORATION (US) | 2011-10-06 | — | — | US | disclosed |
| WO-2009052186-A1 | METABOLOMICS-BASED IDENTIFICATION OF DISEASE-CAUSING AGENTS | GEORGIA TECH RESEARCH CORPORATION (US) | 2009-04-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10100317-B2 | Compositions of matter that reduce pain, shock, and inflammation by blocking linoleic acid metabolites and uses thereof | FABP1, HSPBP1, LTA | MAPT 1136/4885PPARG 312/4885PPARD 547/4885 |
| US-20170204415-A1 | Compositions of Matter that Reduce Pain, Shock, and Inflammation by Blocking Linoleic Acid Metabolites and Uses Thereof | FABP1, HSPBP1, LTA | MAPT 1136/4885PPARG 312/4885PPARD 547/4885 |
| US-20140128588-A1 | COMPOSITIONS OF MATTER THAT REDUCE PAIN, SHOCK, AND INFLAMMATION BY BLOCKING LINOLEIC ACID METABOLITES AND USES THEREOF | FABP1, HSPBP1, LTA | MAPT 1136/4885PPARG 312/4885PPARD 547/4885 |
| US-20160045610-A1 | COMPOSITIONS OF MATTER THAT REDUCE PAIN, SHOCK, AND INFLAMMATION BY BLOCKING LINOLEIC ACID METABOLITES AND USES THEREOF | FABP1, HSPBP1, LTA | MAPT 1136/4885PPARG 312/4885PPARD 547/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.