SCHEMBL267874

SCHEMBL267874

CCCCCC=CCC1OC1CCCCCCCC(=O)O.CCCCC[C@H]1O[C@H]1C/C=C\CCCCCCCC(=O)O

nearest known ligand 0.82

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.75
PPARG P37231 5/20 0.64
PPARD Q03181 5/20 0.64
PPARA Q07869 5/20 0.64
F7 P08709 5/20 0.64
F3 P13726 5/20 0.64
TERT O14746 3/20 0.64
PTPN1 P18031 3/20 0.64
HSD17B10 Q99714 3/20 0.64
FABP4 P15090 3/20 0.64
BLM P54132 2/20 0.64
LMNA P02545 2/20 0.64
ALOX15 P16050 2/20 0.64
DUSP3 P51452 2/20 0.64
CYP19A1 P11511 2/20 0.64
PTGS1 P23219 2/20 0.64
NR4A2 P43354 2/20 0.64
SIRT6 Q8N6T7 2/20 0.64
PTPN7 P35236 2/20 0.64
TDP1 Q9NUW8 2/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2507620 1.00 MAPT (0.75) MAPTPPARGPPARDPPARAF7
SCHEMBL15287028 1.00 MAPT (0.75) MAPTPPARGPPARDPPARAF7
SCHEMBL15808604 1.00 MAPT (0.75) MAPTPPARGPPARDPPARAF7
SCHEMBL1593964 1.00 MAPT (0.75) MAPTPPARGPPARDPPARAF7
SCHEMBL3679458 1.00 MAPT (0.75) MAPTPPARGPPARDPPARAF7
SCHEMBL2228907 1.00 MAPT (0.75) MAPTPPARGPPARDPPARAF7
SCHEMBL2566928 1.00 MAPT (0.75) MAPTPPARGPPARDPPARAF7
SCHEMBL3507735 1.00 MAPT (0.75) MAPTPPARGPPARDPPARAF7
SCHEMBL55116 1.00 MAPT (0.75) MAPTPPARGPPARDPPARAF7
SCHEMBL2228910 1.00 MAPT (0.75) MAPTPPARGPPARDPPARAF7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8134046-B2 Method for producing arachidonic acid and/or eicosapentaenoic acid in useful transgenic plants BASF PLANT SCIENCE GMBH (DE) 2012-03-13 US disclosed
EP-1937805-B1 PROCESS FOR THE PRODUCTION OF ARACHIDONIC ACID AND/OR EICOSAPENTAENOIC ACID BASF PLANT SCIENCE GMBH (DE) 2012-02-22 EP disclosed
US-20120017332-A1 PROCESS FOR THE PRODUCTION OF ARACHIDONIC ACID AND/OR EICOSAPENTAENOIC ACID BASF PLANT SCIENCE GMBH (DE) 2012-01-19 US disclosed
US-20120011618-A1 PROCESS FOR THE PRODUCTION OF ARACHIDONIC ACID AND/OR EICOSAPENTAENOIC ACID BASF PLANT SCIENCE GMBH (DE) 2012-01-12 US disclosed
EP-2388332-A1 Process for the production of delta5-unsaturated fatty acids in transgenic organisms BASF Plant Science GmbH (DE) 2011-11-23 EP disclosed
US-20110277043-A1 Desaturases and Process for the Production of Polyunsaturated Fatty Acids in Transgenic Organisms BASF PLANT SCIENCE COMPANY GMBH (DE) 2011-11-10 US disclosed
US-8049064-B2 Method for producing polyunsaturated C20- and C22-fatty acids with at least four double bonds in transgenic plants BASF PLANT SCIENCE GMBH (DE) 2011-11-01 US disclosed
EP-2376638-A2 DESATURASES AND PROCESS FOR THE PRODUCTION OF POLYUNSATURATED FATTY ACIDS IN TRANSGENIC ORGANISMS BASF Plant Science GmbH (DE) 2011-10-19 EP disclosed
US-8037577-B2 Tool handle INFAR INDUSTRIAL CO., LTD. (TW) 2011-10-18 US disclosed
EP-2366781-A1 Process for the production of delta5-unsaturated fatty acids in transgenic organisms BASF Plant Science GmbH (DE) 2011-09-21 EP disclosed
US-8017839-B2 Process for the production of arachidonic acid and/or eicosapentaenoic acid BASF PLANT SCIENCE GMBH (DE) 2011-09-13 US disclosed
US-20110138490-A1 DESATURASE AND METHOD FOR THE PRODUCTION OF POLYUNSATURATED FATTY ACIDS IN TRANSGENIC ORGANISMS ROTHAMSTED RESEARCH LTD. 2011-06-09 US disclosed
EP-2281051-A1 DESATURASE AND METHOD FOR THE PRODUCTION OF POLYUNSATURATED FATTY ACIDS IN TRANSGENIC ORGANISMS Rothamsted Research Limited (GB) 2011-02-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110277043-A1 Desaturases and Process for the Production of Polyunsaturated Fatty Acids in Transgenic Organisms FASN, FADS2, FADS1 MAPT 4113/4885PPARG 840/4885PPARD 544/4885
US-20110138490-A1 DESATURASE AND METHOD FOR THE PRODUCTION OF POLYUNSATURATED FATTY ACIDS IN TRANSGENIC ORGANISMS ELOVL3, FASN, ELOVL5 MAPT 4083/4885PPARG 338/4885PPARD 312/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.