Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 9/20 | 0.36 |
| ▸ | S1PR5 | Q9H228 | 9/20 | 0.36 |
| ▸ | APLNR | P35414 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25076300 | 0.82 | BRD4 (0.35) | DPP4SMN1; SMN2 | |
| SCHEMBL30767404 | 0.80 | HSD11B1 (0.39) | S1PR1S1PR5HSD11B1 | |
| SCHEMBL18566778 | 0.77 | APLNR (0.39) | APLNRMAPTCYP2C19POLB | |
| SCHEMBL3415496 | 0.75 | — | — | |
| SCHEMBL25153264 | 0.74 | DPP4 (0.31) | DPP4 | |
| SCHEMBL21191254 | 0.73 | KHK (0.31) | DPP4 | |
| SCHEMBL22329111 | 0.73 | DPP4 (0.31) | DPP4 | |
| Hydrochloric Acid SCHEMBL28769763 | 0.73 | S1PR5 (0.47) | S1PR1S1PR5S1PR3SMN1; SMN2S1PR4 | |
| SCHEMBL28950942 | 0.73 | CYP2C19 (0.37) | APLNRMAPTDPP4CYP2C19 | |
| SCHEMBL30636654 | 0.72 | ATM (0.34) | DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119677733-A | Bicyclic tetrahydrothiazepine derivatives | 豪夫迈·罗氏有限公司 | 2025-03-21 | — | — | CN | disclosed |
| EP-4387980-A1 | INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOF | Pardes Biosciences, Inc. (US) | 2024-06-26 | — | — | EP | disclosed |
| WO-2023023631-A1 | INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOF | Pardes Biosciences, Inc. (US) | 2023-02-23 | — | — | WO | disclosed |
| WO-2023023631-A1 | INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOF | Pardes Biosciences, Inc. (US) | 2023-02-23 | — | — | WO | disclosed |