SCHEMBL25076648

SCHEMBL25076648

CCCCC/C=C\C/C=C\CCCCCCCCOSC

nearest known ligand 0.61

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.51
CNR1 P21554 1/20 0.51
CNR2 P34972 1/20 0.51
TRPV1 Q8NER1 1/20 0.48
DUSP3 P51452 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21042083 0.84 ALDH1A1 (0.50) ALDH1A1CNR1CNR2TRPV1
SCHEMBL21842925 0.82 THRB (0.44)
SCHEMBL28047125 0.82 THRB (0.44)
SCHEMBL12474184 0.80 ALDH1A1 (0.58) ALDH1A1CNR1CNR2TRPV1DUSP3
SCHEMBL6261092 0.80 ALDH1A1 (0.58) ALDH1A1CNR1CNR2TRPV1DUSP3
SCHEMBL20503612 0.79 TRPV1 (0.70) ALDH1A1TRPV1DUSP3
SCHEMBL6476959 0.79 TRPV1 (0.70) ALDH1A1TRPV1DUSP3
SCHEMBL6477509 0.79 TRPV1 (0.70) ALDH1A1TRPV1DUSP3
SCHEMBL59342 0.79 TRPV1 (0.70) ALDH1A1TRPV1DUSP3
SCHEMBL24283496 0.79 TRPV1 (0.70) ALDH1A1TRPV1DUSP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023023410-A9 IONIZABLE LIPIDS, LIPID NANOPARTICLES FOR MRNA DELIVERY AND METHODS OF MAKING THE SAME UNIVERSITY OF CINCINNATI (US) 2023-05-11 WO disclosed
WO-2023023410-A2 IONIZABLE LIPIDS, LIPID NANOPARTICLES FOR MRNA DELIVERY AND METHODS OF MAKING THE SAME UNIVERSITY OF CINCINNATI (US) 2023-02-23 WO disclosed