Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLRMT | O00411 | 1/20 | 0.42 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | ADK | P55263 | 4/20 | 0.33 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.31 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.31 |
| ▸ | AKT1 | P31749 | 1/20 | 0.31 |
| ▸ | AKT2 | P31751 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25077260 | 0.97 | POLRMT (0.44) | POLRMTFGFR1CYP3A4CYP2D6ADK | |
| SCHEMBL25764493 | 0.86 | POLRMT (0.37) | POLRMTPIK3R1AKT1AKT2PIK3CA | |
| SCHEMBL26286033 | 0.86 | POLRMT (0.37) | POLRMTFGFR1PIK3R1AKT1AKT2 | |
| SCHEMBL25077308 | 0.86 | POLRMT (0.37) | POLRMTPIK3R1AKT1AKT2PIK3CA | |
| SCHEMBL25773415 | 0.86 | POLRMT (0.37) | POLRMTPIK3R1AKT1AKT2PIK3CA | |
| SCHEMBL25077210 | 0.84 | POLRMT (0.51) | POLRMTFGFR1CYP3A4CYP2D6ADK | |
| SCHEMBL26285621 | 0.84 | POLRMT (0.51) | POLRMTFGFR1CYP3A4CYP2D6ADK | |
| SCHEMBL25077162 | 0.83 | POLRMT (0.35) | POLRMTPIK3R1AKT1AKT2PIK3CA | |
| SCHEMBL25077601 | 0.83 | POLRMT (0.35) | POLRMTPIK3R1AKT1AKT2PIK3CA | |
| SCHEMBL25773695 | 0.82 | POLRMT (0.34) | POLRMTPIK3R1AKT1AKT2PIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023023527-A1 | PHOSPHOLIPID COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | GILEAD SCIENCES, INC. (US) | 2023-02-23 | — | — | WO | disclosed |