Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
| ▸ | MGLL | Q99685 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | RPA1 | P27694 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25078330 | 0.86 | HPGD (0.51) | SMN1; SMN2CYP1A2CYP2C9CYP2C19HPGD | |
| SCHEMBL25078609 | 0.83 | HPGD (0.52) | SMN1; SMN2CYP1A2CYP2C9CYP2C19HPGD | |
| SCHEMBL10568581 | 0.81 | KDM4E (0.51) | SMN1; SMN2CYP1A2CYP2C9CYP2C19HPGD | |
| SCHEMBL13239857 | 0.80 | RPA1 (0.70) | SMN1; SMN2FAAHMGLLMEN1KMT2A | |
| SCHEMBL28644955 | 0.80 | HPGD (0.50) | SMN1; SMN2CYP1A2CYP2C9CYP2C19HPGD | |
| SCHEMBL69400 | 0.80 | SMN1; SMN2 (0.60) | SMN1; SMN2CYP1A2CYP2C9CYP2C19HPGD | |
| SCHEMBL11649636 | 0.78 | HPGD (0.59) | SMN1; SMN2CYP1A2CYP2C9CYP2C19HPGD | |
| SCHEMBL25078566 | 0.77 | LMNA (0.44) | SMN1; SMN2CYP1A2CYP2C9CYP2C19MAPT | |
| SCHEMBL25078205 | 0.77 | SMN1; SMN2 (0.57) | SMN1; SMN2CYP1A2CYP2C9CYP2C19HPGD | |
| SCHEMBL19186324 | 0.76 | SMN1; SMN2 (0.41) | SMN1; SMN2CYP1A2CYP2C9CYP2C19HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4667458-A1 | PHARMACEUTICAL COMPOSITION FOR TREATMENT OF CANCER, COMPRISING SOS1 INHIBITOR AND ANTICANCER DRUG | Kanaph Therapeutics Inc. (KR) | 2025-12-24 | — | — | EP | disclosed |
| CN-118119600-A | SOS1 inhibitors and uses thereof | 治纳辅医药科技有限公司 | 2024-05-31 | — | — | CN | disclosed |
| WO-2023022497-A1 | SOS1 INHIBITOR AND USE THEREOF | 주식회사 카나프테라퓨틱스 | 2023-02-23 | — | — | WO | disclosed |