Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HB | P07237 | 4/20 | 0.49 |
| ▸ | TP53 | P04637 | 6/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 6/20 | 0.47 |
| ▸ | LMNA | P02545 | 5/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.47 |
| ▸ | BRAF | P15056 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 6/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30253616 | 1.00 | P4HB (0.49) | P4HBTP53ALOX12LMNAALOX15 | |
| SCHEMBL30253796 | 0.88 | ALOX12 (0.51) | P4HBTP53ALOX12LMNAALOX15 | |
| SCHEMBL25079000 | 0.88 | ALOX12 (0.51) | P4HBTP53ALOX12LMNAALOX15 | |
| SCHEMBL1240268 | 0.85 | P4HB (0.69) | P4HBTP53ALOX12LMNAALOX15 | |
| SCHEMBL25079050 | 0.84 | ALDH1A1 (0.39) | P4HBTP53ALOX12LMNAALOX15 | |
| SCHEMBL25078945 | 0.84 | ALDH1A1 (0.39) | P4HBTP53ALOX12LMNAALOX15 | |
| SCHEMBL30253648 | 0.84 | ALDH1A1 (0.39) | P4HBTP53ALOX12LMNAALOX15 | |
| SCHEMBL30253755 | 0.84 | ALDH1A1 (0.39) | P4HBTP53ALOX12LMNAALOX15 | |
| SCHEMBL25079080 | 0.84 | P4HB (0.46) | P4HBTP53ALOX12LMNAALOX15 | |
| SCHEMBL11955339 | 0.84 | ALDH1A1 (0.55) | P4HBTP53ALOX12LMNAALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023020534-A1 | COMPOUNDS AND THEIR USES AS MIF INHIBITORS | NANJING IMMUNOPHAGE BIOTECH CO., LTD (CN) | 2023-02-23 | — | — | WO | disclosed |