Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.43 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.43 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20204386 | 0.86 | ALDH1A1 (0.49) | ALDH1A1MAPK1L3MBTL1LMNAALOX5 | |
| SCHEMBL14072159 | 0.85 | ALDH1A1 (0.53) | ALDH1A1MAPK1L3MBTL1LMNAALOX5 | |
| SCHEMBL23205643 | 0.83 | ALDH1A1 (0.54) | ALDH1A1MAPK1L3MBTL1LMNAALOX5 | |
| SCHEMBL6940118 | 0.81 | ALDH1A1 (0.53) | ALDH1A1MAPK1L3MBTL1LMNAKMT2A | |
| SCHEMBL13407447 | 0.80 | ALDH1A1 (0.58) | ALDH1A1MAPK1L3MBTL1LMNAKMT2A | |
| Hydrochloric Acid SCHEMBL7773306 | 0.79 | ALDH1A1 (0.51) | ALDH1A1MAPK1L3MBTL1LMNAKMT2A | |
| SCHEMBL14439282 | 0.79 | ALDH1A1 (0.53) | ALDH1A1MAPK1L3MBTL1LMNAALOX5 | |
| SCHEMBL6050753 | 0.78 | ALDH1A1 (0.49) | ALDH1A1MAPK1L3MBTL1LMNAALOX5 | |
| SCHEMBL6050747 | 0.78 | ALDH1A1 (0.49) | ALDH1A1MAPK1L3MBTL1LMNAALOX5 | |
| SCHEMBL7366351 | 0.78 | CCR6 (0.53) | ALDH1A1MAPK1L3MBTL1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023023261-A1 | RADIOFLUORINATED AGENTS FOR PET IMAGING SELECTIVELY TARGETING FIBROBLAST ACTIVATION PROTEIN | TRUSTEES OF TUFTS COLLEGE (US) | 2023-02-23 | — | — | WO | disclosed |