SCHEMBL6940118

SCHEMBL6940118

CC(=O)N(N)CCC(=O)OCc1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.53
MAPK1 P28482 2/20 0.51
L3MBTL1 Q9Y468 2/20 0.51
LMNA P02545 1/20 0.50
HCAR2 Q8TDS4 1/20 0.44
TDP1 Q9NUW8 2/20 0.44
SLC6A2 P23975 1/20 0.44
SLC6A3 Q01959 1/20 0.44
KMT2A Q03164 1/20 0.44
CDC25B P30305 1/20 0.43
CA12 O43570 2/20 0.43
CA1 P00915 2/20 0.43
CA2 P00918 2/20 0.43
CA9 Q16790 2/20 0.43
SLC15A1 P46059 2/20 0.43
MAPT P10636 1/20 0.42
HPGD P15428 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7773306 0.98 ALDH1A1 (0.51) ALDH1A1MAPK1L3MBTL1LMNAHCAR2
SCHEMBL7773328 0.86 ALDH1A1 (0.53) ALDH1A1MAPK1L3MBTL1LMNAHCAR2
Hydrochloric Acid SCHEMBL7773343 0.85 ALDH1A1 (0.51) ALDH1A1MAPK1L3MBTL1LMNAHCAR2
SCHEMBL7769197 0.81 ALOX5 (0.49) ALDH1A1MAPK1L3MBTL1LMNAKMT2A
SCHEMBL13407447 0.81 ALDH1A1 (0.58) ALDH1A1MAPK1L3MBTL1LMNATDP1
SCHEMBL25080353 0.81 ALDH1A1 (0.51) ALDH1A1MAPK1L3MBTL1LMNAHCAR2
Hydrochloric Acid SCHEMBL7773270 0.80 ALOX5 (0.48) ALDH1A1MAPK1L3MBTL1LMNAKMT2A
SCHEMBL6942127 0.79 ABCB1 (0.49) ALDH1A1MAPK1L3MBTL1LMNATDP1
SCHEMBL17177612 0.79 ALDH1A1 (0.51) ALDH1A1MAPK1L3MBTL1LMNATDP1
SCHEMBL20204386 0.78 ALDH1A1 (0.49) ALDH1A1MAPK1L3MBTL1LMNAHCAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6538007-B1 Hydrates and method of antogonizing glycoprotein IIb/IIIa activity using these compounds is also disclosed. antagonist, inhibitor of blood platelets aggregation and inhibitor of the binding of fibrinogen to blood platelets. FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2003-03-25 US disclosed
EP-1121346-A1 NEW PROCESSES FOR PRODUCING BETA-ALANINE DERIVATIVE FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2001-08-08 EP disclosed
WO-2000021932-A1 NEW PROCESSES FOR PRODUCING β-ALANINE DERIVATIVE FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2000-04-20 WO disclosed