Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | SCN1A | P35498 | 1/20 | 0.39 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.39 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30035926 | 1.00 | KMO (0.40) | KMOPTGDR2CYP1A2LMNACYP2D6 | |
| SCHEMBL27182061 | 1.00 | KMO (0.40) | KMOPTGDR2CYP1A2LMNACYP2D6 | |
| SCHEMBL25429111 | 1.00 | KMO (0.40) | KMOPTGDR2CYP1A2LMNACYP2D6 | |
| SCHEMBL29771760 | 1.00 | KMO (0.40) | KMOPTGDR2CYP1A2LMNACYP2D6 | |
| SCHEMBL2508226 | 0.99 | KMT2A (0.39) | KMOPTGDR2CYP1A2LMNACYP2D6 | |
| SCHEMBL2508456 | 0.89 | KMO (0.39) | KMOPTGDR2CYP1A2LMNACYP2D6 | |
| SCHEMBL2495971 | 0.89 | KMO (0.39) | KMOPTGDR2CYP1A2LMNACYP2D6 | |
| SCHEMBL2511736 | 0.89 | KMO (0.39) | KMOPTGDR2CYP1A2LMNACYP2D6 | |
| SCHEMBL2507534 | 0.87 | KMT2A (0.38) | KMOPTGDR2CYP1A2LMNACYP2D6 | |
| SCHEMBL2886892 | 0.86 | PTGDR2 (0.40) | KMOPTGDR2CYP1A2LMNACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12528762-B2 | Catalyst composition for polyolefin polymers | W.R. GRACE & CO.-CONN (US) | 2026-01-20 | — | — | US | disclosed |
| US-20250109220-A1 | Olefin Polymerization Catalyst Comprising Magnesium, Titanium, an Epoxy Compound and an Internal Electron Donor, Such as a 1,2-Phenylene Dibenzoate-Based Compound | W. R. GRACE & CO.-CONN. | 2025-04-03 | — | — | US | disclosed |
| EP-4473023-A1 | OLEFIN POLYMERIZATION CATALYST COMPRISING MAGNESIUM, TITANIUM, AN EPOXY COMPOUND AND AN INTERNAL ELECTRON DONOR, SUCH AS A 1,2-PHENYLENE DIBENZOATE-BASED COMPOUND | W.R. GRACE & CO.-CONN. (US) | 2024-12-11 | — | — | EP | disclosed |
| CN-118974105-A | Olefin polymerization catalyst comprising magnesium, titanium, epoxy compounds and internal electron donors such as compounds based on 1, 2-phenylene dibenzoate | 格雷斯公司 | 2024-11-15 | — | — | CN | disclosed |
| US-11993700-B2 | Catalyst system for the production of polyolefins and method of making and using same | W.R. Grace & Co.—Conn. (US) | 2024-05-28 | — | — | US | disclosed |
| WO-2023147021-A1 | OLEFIN POLYMERIZATION CATALYST COMPRISING MAGNESIUM, TITANIUM, AN EPOXY COMPOUND AND AN INTERNAL ELECTRON DONOR, SUCH AS A 1,2-PHENYLENE DIBENZOATE-BASED COMPOUND | W.R. GRACE & CO.-CONN. (US) | 2023-08-03 | — | — | WO | disclosed |
| WO-2023147021-A1 | OLEFIN POLYMERIZATION CATALYST COMPRISING MAGNESIUM, TITANIUM, AN EPOXY COMPOUND AND AN INTERNAL ELECTRON DONOR, SUCH AS A 1,2-PHENYLENE DIBENZOATE-BASED COMPOUND | W.R. GRACE & CO.-CONN. (US) | 2023-08-03 | — | — | WO | disclosed |
| CN-115160459-A | Catalyst systems for producing polyolefins and methods of making and using the same | 格雷斯公司 | 2022-10-11 | — | — | CN | disclosed |
| US-20220220060-A1 | CATALYST COMPOSITION FOR POLYOLEFIN POLYMERS | W.R. GRACE & CO.-CONN (US) | 2022-07-14 | — | — | US | disclosed |
| US-20220220060-A1 | CATALYST COMPOSITION FOR POLYOLEFIN POLYMERS | W.R. GRACE & CO.-CONN (US) | 2022-07-14 | — | — | US | disclosed |
| EP-3507311-A1 | CATALYST SYSTEM FOR THE PRODUCTION OF POLYOLEFINS AND METHOD OF MAKING AND USING SAME | W. R. Grace & Co. - Conn. (US) | 2019-07-10 | — | — | EP | disclosed |
| US-20190194438-A1 | Catalyst System For The Production Of Polyolefins And Method Of Making And Using Same | W. R. GRACE & CO.-CONN. | 2019-06-27 | — | — | US | disclosed |
| CN-109843933-A | Catalyst systems for producing polyolefins and methods of making and using the same | 格雷斯公司 | 2019-06-04 | — | — | CN | disclosed |
| WO-2018045020-A1 | CATALYST SYSTEM FOR THE PRODUCTION OF POLYOLEFINS AND METHOD OF MAKING AND USING SAME | W.R. GRACE & CO. - CONN (US) | 2018-03-08 | — | — | WO | disclosed |
| CN-104860826-A | Production of substituted phenylene aromatic diesters | DOW GLOBAL TECHNOLOGIES LLC | 2015-08-26 | — | — | CN | disclosed |
| CN-102741215-B | Production of substituted phenylene aromatic diesters | DOW GLOBAL TECHNOLOGIES INC | 2015-04-29 | — | — | CN | disclosed |
| US-8604235-B2 | Production of substituted phenylene aromatic diesters and compositions | DOW GLOBAL TECHNOLOGIES LLC (US) | 2013-12-10 | — | — | US | disclosed |
| EP-2376423-A1 | PRODUCTION OF SUBSTITUTED PHENYLENE AROMATIC DIESTERS | Dow Global Technologies LLC (US) | 2011-10-19 | — | — | EP | disclosed |
| US-20100204506-A1 | Production of Substituted Phenylene Aromatic Diesters and Compositions | W. R. GRACE & CO.-CONN. | 2010-08-12 | — | — | US | disclosed |
| WO-2010078519-A1 | PRODUCTION OF SUBSTITUTED PHENYLENE AROMATIC DIESTERS | DOW GLOBAL TECHNOLOGIES INC. (US) | 2010-07-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12528762-B2 | Catalyst composition for polyolefin polymers | TKT, TCP1, PPT1 | KMO 313/4885PTGDR2 1852/4885CYP1A2 978/4885 |
| US-20220220060-A1 | CATALYST COMPOSITION FOR POLYOLEFIN POLYMERS | DNTT, TKT, APRT | KMO 518/4885PTGDR2 4005/4885CYP1A2 2591/4885 |
| US-20100204506-A1 | Production of Substituted Phenylene Aromatic Diesters and Compositions | PAH, DDC, DDT | KMO 283/4885PTGDR2 1971/4885CYP1A2 76/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.