SCHEMBL25083082

SCHEMBL25083082

CC(C)NC(=O)CCCC(=O)C(C)C

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FAAH O00519 2/20 0.61
MEN1 O00255 1/20 0.61
MAPK1 P28482 1/20 0.61
KMT2A Q03164 1/20 0.61
KDM4E B2RXH2 2/20 0.43
ALDH1A1 P00352 2/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
HPGD P15428 3/20 0.42
HSD17B10 Q99714 1/20 0.42
SMN1; SMN2 Q16637 2/20 0.41
NLRP1 Q9C000 1/20 0.41
EPHX2 P34913 1/20 0.40
TSHR P16473 1/20 0.38
POLB P06746 1/20 0.37
DNM1 Q05193 1/20 0.36
CHRM5 P08912 1/20 0.36
CHRM3 P20309 1/20 0.36
THRB P10828 1/20 0.35
HDAC3 O15379 1/20 0.35
HDAC4 P56524 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23772929 0.93 FAAH (0.70) FAAHMEN1MAPK1KMT2AKDM4E
SCHEMBL22769011 0.93 FAAH (0.70) FAAHMEN1MAPK1KMT2AKDM4E
SCHEMBL24530783 0.93 FAAH (0.70) FAAHMEN1MAPK1KMT2AKDM4E
SCHEMBL5909190 0.91 FAAH (0.71) FAAHMEN1MAPK1KMT2AKDM4E
SCHEMBL22280196 0.88 MEN1 (0.52) FAAHMEN1MAPK1KMT2AKDM4E
SCHEMBL12934925 0.85 FAAH (0.78) FAAHMEN1MAPK1KMT2AKDM4E
SCHEMBL13373653 0.85 FAAH (0.59) FAAHMEN1MAPK1KMT2AKDM4E
SCHEMBL12934924 0.83 FAAH (0.83) FAAHMEN1MAPK1KMT2AHPGD
SCHEMBL12934930 0.83 FAAH (0.83) FAAHMEN1MAPK1KMT2AHPGD
SCHEMBL12934928 0.83 FAAH (0.83) FAAHMEN1MAPK1KMT2AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240238458-A1 COMPOUNDS TARGETING FIBROBLAST-ACTIVATION PROTEIN AND METHODS OF USE THEREOF PURDUE RESEARCH FOUNDATION 2024-07-18 US disclosed
WO-2024049769-A2 PATTERNED RELEASE LAYERS, AND METHODS OF MAKING AND USING THEM IN DEVICE MANUFACTURING TERECIRCUITS CORPORATION (US) 2024-03-07 WO disclosed
US-20230333475-A1 COMPOSITE MATERIAL COMPRISING A RELEASE MATERIAL AND A THERMOPOLYMER MATERIAL, AND USES THEREOF TERECIRCUITS CORPORATION 2023-10-19 US disclosed
US-20230333475-A1 COMPOSITE MATERIAL COMPRISING A RELEASE MATERIAL AND A THERMOPOLYMER MATERIAL, AND USES THEREOF TERECIRCUITS CORPORATION 2023-10-19 US disclosed
WO-2023200975-A1 COMPOSITE MATERIAL COMPRISING A RELEASE MATERIAL AND A THERMOPOLYMER MATERIAL, AND USES THEREOF TERECIRCUITS CORPORATION (US) 2023-10-19 WO disclosed
US-20230248835-A1 COMPOUNDS, COMPOSITIONS, AND METHODS FOR THE TREATMENT OF FIBROTIC DISEASES AND CANCER PURDUE RESEARCH FOUNDATION 2023-08-10 US disclosed
US-20230158150-A1 COMPOUND COMPRISING A NUCLEIC ACID AND A HALF-LIFE EXTENSION MOTIF NOVARTIS AG (CH) 2023-05-25 US disclosed
US-20230158153-A1 PI3 KINASE INHIBITORS AND USES THEREOF PURDUE RESEARCH FOUNDATION 2023-05-25 US disclosed
US-20230130004-A1 RELEASE LAYER COMPOSITION FOR TRANSFER OF COMPONENTS TERECIRCUITS CORPORATION 2023-04-27 US disclosed
US-20230130004-A1 RELEASE LAYER COMPOSITION FOR TRANSFER OF COMPONENTS TERECIRCUITS CORPORATION 2023-04-27 US disclosed
WO-2023023554-A1 RELEASE LAYER COMPOSITION FOR TRANSFER OF COMPONENTS TERECIRCUITS CORPORATION (US) 2023-02-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230248835-A1 COMPOUNDS, COMPOSITIONS, AND METHODS FOR THE TREATMENT OF FIBROTIC DISEASES AND CANCER TLR9, TLR8, TLR7 FAAH 1857/4885MEN1 3475/4885MAPK1 1890/4885
US-20230158153-A1 PI3 KINASE INHIBITORS AND USES THEREOF MMP1, PIK3CA, AKT2 FAAH 4065/4885MEN1 3624/4885MAPK1 199/4885
US-20240238458-A1 COMPOUNDS TARGETING FIBROBLAST-ACTIVATION PROTEIN AND METHODS OF USE THEREOF FAP, FIBP, FGFR1 FAAH 828/4885MEN1 2971/4885MAPK1 1961/4885
US-20230158150-A1 COMPOUND COMPRISING A NUCLEIC ACID AND A HALF-LIFE EXTENSION MOTIF NSUN2, NSUN3, POLM FAAH 3897/4885MEN1 1278/4885MAPK1 4299/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.