Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SRD5A1 | P18405 | 3/20 | 0.34 |
| ▸ | BCHE | P06276 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 8/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11508489 | 0.75 | THRB (0.57) | TDP1NPC1RAB9APOLBCYP2C9 | |
| SCHEMBL29320966 | 0.72 | THRB (0.50) | TDP1NPC1RAB9APOLBCYP2C9 | |
| SCHEMBL1787793 | 0.70 | TDP1 (0.52) | TDP1NPC1RAB9APOLBCYP2C9 | |
| SCHEMBL1952350 | 0.69 | TDP1 (0.54) | TDP1NPC1RAB9APOLBCYP2C9 | |
| SCHEMBL2255475 | 0.67 | NPC1 (0.47) | TDP1NPC1RAB9APOLBCYP2C9 | |
| SCHEMBL15095780 | 0.67 | TDP1 (0.49) | TDP1NPC1RAB9APOLBCYP2C9 | |
| SCHEMBL1833341 | 0.66 | NPC1 (0.54) | TDP1NPC1RAB9APOLBCYP2C9 | |
| SCHEMBL1790593 | 0.66 | KMT2A (0.56) | TDP1NPC1RAB9APOLBCYP2C9 | |
| SCHEMBL26085048 | 0.66 | ELANE (0.61) | TDP1NPC1RAB9APOLBCYP2C9 | |
| SCHEMBL25784281 | 0.66 | THRB (0.43) | TDP1NPC1RAB9APOLBCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11591289-B2 | Aromatic compounds | Xeniopro GmbH (DE) | 2023-02-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11591289-B2 | Aromatic compounds | AHR, TYR, MUSK | TDP1 1153/4885NPC1 4499/4885RAB9A 3345/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.