Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 4/20 | 0.42 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HTR1D | P28221 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | AHR | P35869 | 3/20 | 0.33 |
| ▸ | CMA1 | P23946 | 1/20 | 0.33 |
| ▸ | TYR | P14679 | 1/20 | 0.33 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19954972 | 0.81 | KDM4E (0.36) | BACE1ACACBCYP19A1MEN1POLB | |
| SCHEMBL83970 | 0.74 | AHR (0.50) | CYP19A1MEN1POLBMAPK1KMT2A | |
| SCHEMBL19308895 | 0.73 | EIF4A3 (0.43) | BACE1ACACBCYP19A1MEN1POLB | |
| SCHEMBL826904 | 0.73 | GHSR (0.39) | HTR1DHRH3 | |
| SCHEMBL21524642 | 0.72 | EIF4A3 (0.42) | CYP19A1KDM4EALDH1A1HTR1DSLC6A2 | |
| SCHEMBL12599317 | 0.72 | LOXL2 (0.42) | KDM4EALDH1A1HTR1D | |
| SCHEMBL23653712 | 0.71 | LOXL2 (0.51) | BACE1ACACBCYP19A1MEN1POLB | |
| SCHEMBL30548028 | 0.71 | PTGS2 (0.53) | CYP19A1HTR1DSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL84922 | 0.71 | PTGS2 (0.53) | CYP19A1HTR1DSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL13230548 | 0.70 | BACE1 (0.49) | BACE1ACACBMEN1POLBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230062022-A1 | HETEROCYCLIC COMPOUNDS AS KINASE INHIBITORS | NUVATION BIO INC (US) | 2023-03-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230062022-A1 | HETEROCYCLIC COMPOUNDS AS KINASE INHIBITORS | CDK4, CDK6, CDK8 | BACE1 3570/4885ACACB 2690/4885CYP19A1 1614/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.