Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.71 |
| ▸ | HPGD | P15428 | 2/20 | 0.71 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.71 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.64 |
| ▸ | USP2 | O75604 | 1/20 | 0.64 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.62 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.62 |
| ▸ | BLM | P54132 | 1/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25089904 | 0.88 | KDM4E (0.67) | KDM4EALDH1A1HPGDTDP1ADORA2B | |
| SCHEMBL10614178 | 0.83 | KDM4E (1.00) | KDM4EALDH1A1HPGDTDP1ADORA2B | |
| SCHEMBL8596143 | 0.83 | KDM4E (0.76) | KDM4EALDH1A1HPGDTDP1ADORA2B | |
| SCHEMBL516349 | 0.82 | KDM4E (0.70) | KDM4EALDH1A1HPGDTDP1ADORA2B | |
| SCHEMBL29429838 | 0.82 | KDM4E (0.70) | KDM4EALDH1A1HPGDTDP1ADORA2B | |
| SCHEMBL25090354 | 0.81 | KDM4E (0.72) | KDM4EALDH1A1HPGDTDP1ADORA2B | |
| SCHEMBL2119734 | 0.81 | KDM4E (0.72) | KDM4EALDH1A1HPGDTDP1ADORA2B | |
| SCHEMBL8595301 | 0.81 | KDM4E (0.72) | KDM4EALDH1A1HPGDTDP1ADORA2B | |
| SCHEMBL516485 | 0.80 | ADORA2B (1.00) | KDM4EALDH1A1HPGDTDP1ADORA2B | |
| SCHEMBL1833234 | 0.79 | KDM4E (0.70) | KDM4EALDH1A1HPGDTDP1ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023023867-A1 | COMPOUNDS FOR REDUCING CHOLESTEROL AND TREATING LIVER AND KIDNEY DISEASE | MCMASTER UNIVERSITY (CA) | 2023-03-02 | — | — | WO | disclosed |