SCHEMBL516349

SCHEMBL516349

Cn1c(=O)c2[nH]c(-c3cccc4ccccc34)nc2n(C)c1=O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.70
ALDH1A1 P00352 2/20 0.70
HPGD P15428 2/20 0.70
TDP1 Q9NUW8 1/20 0.70
ADORA2B P29275 2/20 0.66
HSD17B10 Q99714 2/20 0.65
CYP1A2 P05177 1/20 0.65
ADORA3 P0DMS8 1/20 0.65
ADORA2A P29274 1/20 0.65
ADORA1 P30542 1/20 0.65
BLM P54132 1/20 0.65
NPSR1 Q6W5P4 1/20 0.65
USP2 O75604 1/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29429838 1.00 KDM4E (0.70) KDM4EALDH1A1HPGDTDP1ADORA2B
SCHEMBL8596143 0.85 KDM4E (0.76) KDM4EALDH1A1HPGDTDP1ADORA2B
SCHEMBL2119734 0.83 KDM4E (0.72) KDM4EALDH1A1HPGDTDP1ADORA2B
SCHEMBL8595301 0.83 KDM4E (0.72) KDM4EALDH1A1HPGDTDP1ADORA2B
SCHEMBL10614178 0.83 KDM4E (1.00) KDM4EALDH1A1HPGDTDP1ADORA2B
SCHEMBL25090354 0.83 KDM4E (0.72) KDM4EALDH1A1HPGDTDP1ADORA2B
SCHEMBL25089903 0.82 KDM4E (0.71) KDM4EALDH1A1HPGDTDP1ADORA2B
SCHEMBL515556 0.81 KDM4E (0.62) KDM4EALDH1A1HPGDTDP1ADORA2B
SCHEMBL25089896 0.81 ALDH1A1 (0.62) KDM4EALDH1A1HPGDTDP1ADORA2B
SCHEMBL25090658 0.81 PDE5A (0.72) KDM4EALDH1A1HPGDTDP1ADORA2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12310392-B2 Beverage compositions including calcium supplied from aragonite and methods of making the same NANT HOLDINGS IP, LLC (US) 2025-05-27 US disclosed
US-20240381918-A1 Beverage Compositions Including Calcium Supplied From Aragonite And Methods Of Making The Same NANT HOLDINGS IP, LLC 2024-11-21 US disclosed
US-8603555-B2 Methods for quantifying the complete nutritional value of a standard equivalent unit of the nutritional value of one serving of fruits and vegetables (SFV)and for fortifying a base food to contain same for human consumption INNOCENZI MARK A (US) 2013-12-10 US disclosed
US-20120027897-A1 Methods For Quantifying The Complete Nutritional Value Of A Standard Equivalent Unit Of The Nutritional Value Of One Serving Of Fruits & Vegetables (SFV)And For Fortifying A Base Food To Contain Same For Human Consumption INNOCENZI MARK A (US) 2012-02-02 US disclosed
US-8053007-B2 Compositions and methods for fortifying a base food to contain the complete nutritional value of a standard equivalent unit of the nutritional value of one serving of fruits and vegetables (“SFV”) for human consumption Innocenzi, Mark (US) 2011-11-08 US disclosed
US-20110250318-A1 COMPOSITIONS AND METHODS FOR FORTIFYING A BASE FOOD TO CONTAIN THE COMPLETE NUTRITIONAL VALUE OF ONE SERVING OF FRUITS AND VEGTABLES (\"SFV\") FOR HUMAN CONSUMPTION INNOCENZI MARK 2011-10-13 US disclosed
EP-1196050-B2 COMPOSITIONS FOR PROVIDING AND MAINTAINING ENERGY AND MENTAL ALERTNESS FOLGERS COFFEE CO (US) 2010-12-15 EP disclosed
EP-1322185-B1 BEVERAGE COMPOSITIONS COMPRISING ARABINOGALACTAN AND MINERAL SUPPLEMENT PROCTER & GAMBLE (US) 2009-12-09 EP disclosed
CN-100531600-C Hypoglycemic reaction compositions PROCTER & GAMBLE (US) 2009-08-26 CN disclosed
CN-101133834-A Compositions, kits and methods for providing and maintaining energy and mental alertness PROCTER & GAMBLE (US) 2008-03-05 CN disclosed
WO-1996029997-A1 SOFT GELATIN CAPSULE WITH A GELATIN SHELL COMPRISING XANTHINE DERIVATIVE THE PROCTER & GAMBLE COMPANY (US) 1996-10-03 WO disclosed
EP-0165308-B1 ANALGESIC AND ANTI-INFLAMMATORY COMPOSITIONS COMPRISING XANTHINES AND METHODS OF USING SAME Richardson-Vicks, Inc. (US) 1989-03-22 EP disclosed
EP-0167566-A4 ANALGESIC AND ANTI-INFLAMMATORY COMPOSITIONS COMPRISING XANTHINES AND METHODS OF USING SAME. SUNSHINE ABRAHAM (US) 1987-06-29 EP disclosed
EP-0165308-A4 ANALGESIC AND ANTI-INFLAMMATORY COMPOSITIONS COMPRISING XANTHINES AND METHODS OF USING SAME. RICHARDSON VICKS INC (US) 1986-05-16 EP disclosed
US-4567183-A SYNERGISTIC, POTENTIATION ANALGESIC ASSOCIATES (US) 1986-01-28 US disclosed
EP-0167566-A1 ANALGESIC AND ANTI-INFLAMMATORY COMPOSITIONS COMPRISING XANTHINES AND METHODS OF USING SAME SUNSHINE, Abraham (US) 1986-01-15 EP disclosed
EP-0165308-A1 ANALGESIC AND ANTI-INFLAMMATORY COMPOSITIONS COMPRISING XANTHINES AND METHODS OF USING SAME. RICHARDSON VICKS INC (US) 1985-12-27 EP disclosed
US-4558051-A Analgesic and anti-inflammatory compositions comprising xanthines and methods of using same RICHARDSON-VICKS, INC. (US) 1985-12-10 US disclosed
WO-1985002540-A1 ANALGESIC AND ANTI-INFLAMMATORY COMPOSITIONS COMPRISING XANTHINES AND METHODS OF USING SAME RICHARDSON-VICKS, INC. (US) 1985-06-20 WO disclosed
WO-1985002542-A1 ANALGESIC AND ANTI-INFLAMMATORY COMPOSITIONS COMPRISING XANTHINES AND METHODS OF USING SAME SUNSHINE ABRAHAM 1985-06-20 WO disclosed