Known targets — ChEMBL curated mechanism
BTKCACNA1CCACNA1DCACNA1FCACNA1SCACNA2D1CACNA2D2DRD2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQHRH1HTR2AP2RY12
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 1.00 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.62 |
| ▸ | HTR6 | P50406 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | NT5E | P21589 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.52 |
| ▸ | CA1 | P00915 | 2/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA3 | P07451 | 1/20 | 0.52 |
| ▸ | CA4 | P22748 | 1/20 | 0.52 |
| ▸ | CA6 | P23280 | 1/20 | 0.52 |
| ▸ | CA5A | P35218 | 1/20 | 0.52 |
| ▸ | CA7 | P43166 | 1/20 | 0.52 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3409457 | 1.00 | TSHR (1.00) | TSHRSMN1; SMN2POLBCYP2D6HTR6 | |
| Benzene SCHEMBL9751882 | 1.00 | TSHR (1.00) | TSHRSMN1; SMN2POLBCYP2D6HTR6 | |
| SCHEMBL1079321 | 1.00 | TSHR (1.00) | TSHRSMN1; SMN2POLBCYP2D6HTR6 | |
| SCHEMBL30307036 | 1.00 | TSHR (1.00) | TSHRSMN1; SMN2POLBCYP2D6HTR6 | |
| SCHEMBL597672 | 1.00 | TSHR (1.00) | TSHRSMN1; SMN2POLBCYP2D6HTR6 | |
| SCHEMBL125188 | 1.00 | TSHR (1.00) | TSHRSMN1; SMN2POLBCYP2D6HTR6 | |
| SCHEMBL30671620 | 1.00 | TSHR (1.00) | TSHRSMN1; SMN2POLBCYP2D6HTR6 | |
| SCHEMBL30812783 | 1.00 | TSHR (1.00) | TSHRSMN1; SMN2POLBCYP2D6HTR6 | |
| SCHEMBL9871011 | 0.97 | TSHR (0.94) | TSHRSMN1; SMN2POLBCYP2D6HTR6 | |
| Hydrochloric Acid SCHEMBL11436653 | 0.97 | TSHR (0.94) | TSHRSMN1; SMN2POLBCYP2D6HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 455457 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118834118-A | Preparation method and system of o-phenylphenol | 圣奥化学科技有限公司 | 2024-10-25 | — | — | CN | claimed |
| WO-2024217493-A1 | CRYSTALLINE METHIONINE ADENOSYLTRANSFERASE 2a (MAT2A) INHIBITOR AND USES THEREOF | INSILICO MEDICINE IP LIMITED (CN) | 2024-10-24 | — | — | WO | claimed |
| CN-118791516-A | Silane chain extender, preparation method and application thereof | 山东共聚有机硅技术研究院有限公司 | 2024-10-18 | — | — | CN | claimed |
| US-12102630-B2 | Crystalline forms and processes of lenvatinib besylate | SYNTHON B.V. (NL) | 2024-10-01 | — | — | US | claimed |
| CN-118725339-A | Method for extracting lignin in brewer's grains | 华南理工大学 | 2024-10-01 | — | — | CN | claimed |
| CN-118271603-B | Polyaniline nanoparticle and preparation method thereof | 广东腐蚀科学与技术创新研究院 | 2024-09-24 | — | — | CN | claimed |
| US-12097184-B2 | Formulations of psilocin that have enhanced stability | Mind Medicine, Inc. (US) | 2024-09-24 | — | — | US | claimed |
| CN-118684575-A | Isomelanin hydroxyl acylated product, preparation method and pharmaceutical application thereof | 中国医学科学院药物研究所 | 2024-09-24 | — | — | CN | claimed |
| CN-118695759-A | Solar cell, preparation method thereof, power utilization device and energy storage device | 宁德时代新能源科技股份有限公司 | 2024-09-24 | — | — | CN | claimed |
| CN-115872998-B | Preparation method of sildenafil and intermediate thereof | 山东特珐曼药业有限公司 | 2024-09-20 | — | — | CN | claimed |
| US-3936429-A | Reactive polymer | FUJI PHOTO FILM CO., LTD. (JA) | 1976-02-03 | — | — | US | claimed |
| US-3936451-A | Process for producing salts of hexamethylenetetramine | UNITED STATES PIPE AND FOUNDRY COMPANY (US) | 1976-02-03 | — | — | US | claimed |
| US-3935098-A | Adsorbent process for heavy metals | NIPPON SODA CO., LTD. (JA) | 1976-01-27 | — | — | US | claimed |
| US-3935129-A | ALKALI METAL SILICATE, UREA, GLYCERINE, TRIETHANOLAMINE, ANIONIC AND NONIONIC DETERGENT | JABALEE WALTER J | 1976-01-27 | — | — | US | claimed |
| US-3933509-A | Photo-polymerizable composition containing an acid salt of an indolinobenzospiropyran | FUJI PHOTO FILM CO., LTD. (JA) | 1976-01-20 | — | — | US | claimed |
| US-3933902-A | Method for the optical resolution of DL-αphenylglycine | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JA) | 1976-01-20 | — | — | US | claimed |
| US-3932166-A | Landfill and soil conditioner | VIGNOVICH MARTIN | 1976-01-13 | — | — | US | claimed |
| US-3931262-A | Hydrophilic and difficultly volatile biocidal triorganotin compounds | CIBA-GEIGY CORPORATION (US) | 1976-01-06 | — | — | US | claimed |
| US-3931215-A | OPTICAL BRIGHTENERS | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-01-06 | — | — | US | claimed |
| US-3931386-A | Process for producing drawn or undrawn flame-resistant, anti-fusing cured phenolic continuous filaments | NIPPON KYNOL INCORPORATED (JA) | 1976-01-06 | — | — | US | claimed |