Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 1/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.30 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.30 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25091051 | 0.81 | HCRTR1 (0.33) | HCRTR1HCRTR2ATMNPSR1CYP1A2 | |
| SCHEMBL25091049 | 0.81 | NPSR1 (0.36) | HCRTR1HCRTR2ATMNPSR1KMT2A | |
| SCHEMBL25091056 | 0.78 | NPC1 (0.36) | HCRTR1HCRTR2KDM4EL3MBTL1NPSR1 | |
| SCHEMBL29324752 | 0.77 | GSK3B (0.39) | HCRTR1HCRTR2ATMGSK3BCYP1A2 | |
| SCHEMBL25527223 | 0.72 | GSK3B (0.38) | HCRTR1HCRTR2L3MBTL1PDE10AGSK3B | |
| SCHEMBL28619610 | 0.72 | HSD17B10 (0.40) | HCRTR1HCRTR2NPSR1GSK3B | |
| SCHEMBL18538040 | 0.72 | HPGD (0.40) | HCRTR1HCRTR2KDM4EL3MBTL1NPSR1 | |
| SCHEMBL25091062 | 0.71 | HCRTR1 (0.43) | HCRTR1HCRTR2KDM4EL3MBTL1NPSR1 | |
| SCHEMBL31298626 | 0.70 | HCRTR1 (0.40) | HCRTR1HCRTR2NPSR1 | |
| SCHEMBL18538049 | 0.70 | ALDH1A1 (0.42) | KDM4ENPSR1MEN1KMT2AGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230060334-A1 | COMPOUNDS FOR TARGETED DEGRADATION OF BRD9 | C4 THERAPEUTICS, INC. (US) | 2023-03-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230060334-A1 | COMPOUNDS FOR TARGETED DEGRADATION OF BRD9 | BRD9, BRD1, BRWD1 | HCRTR1 4593/4885HCRTR2 4706/4885ATM 1821/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.