Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | SPR | P35270 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.30 |
| ▸ | AURKA | O14965 | 1/20 | 0.30 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.30 |
| ▸ | JAK2 | O60674 | 1/20 | 0.30 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.30 |
| ▸ | PAK4 | O96013 | 1/20 | 0.30 |
| ▸ | ABL1 | P00519 | 1/20 | 0.30 |
| ▸ | CSF1R | P07333 | 1/20 | 0.30 |
| ▸ | RET | P07949 | 1/20 | 0.30 |
| ▸ | IGF1R | P08069 | 1/20 | 0.30 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.30 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.30 |
| ▸ | PRKACA | P17612 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27259567 | 0.85 | GSK3B (0.40) | HSD17B10GSK3BPOLBMAOB | |
| SCHEMBL29324752 | 0.81 | GSK3B (0.39) | GSK3BPOLBSPRHCRTR1HCRTR2 | |
| SCHEMBL18538040 | 0.80 | HPGD (0.40) | HSD17B10GSK3BPOLBSPRNPSR1 | |
| SCHEMBL25527223 | 0.80 | GSK3B (0.38) | GSK3BPOLBSPRHCRTR1HCRTR2 | |
| SCHEMBL18538049 | 0.78 | ALDH1A1 (0.42) | GSK3BPOLBMAOBNPSR1 | |
| SCHEMBL6952100 | 0.77 | SPR (0.46) | HSD17B10GSK3BPOLBSPRCHEK1 | |
| SCHEMBL30924204 | 0.77 | SPR (0.46) | HSD17B10GSK3BPOLBSPRCHEK1 | |
| SCHEMBL12703712 | 0.76 | HSD17B10 (0.46) | HSD17B10GSK3BPOLBSPRMAOB | |
| SCHEMBL31149372 | 0.76 | HSD17B10 (0.42) | HSD17B10GSK3BPOLBSPRMAOB | |
| SCHEMBL12703617 | 0.76 | HSD17B10 (0.42) | HSD17B10GSK3BPOLBSPRMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108602799-B | Kinase inhibitor | 上海复尚慧创医药研究有限公司 | 2021-08-03 | — | — | CN | disclosed |