Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | SPR | P35270 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28619610 | 0.81 | HSD17B10 (0.40) | GSK3BSPRPOLBHCRTR1HCRTR2 | |
| SCHEMBL25527223 | 0.81 | GSK3B (0.38) | GSK3BSPRPOLBHCRTR1HCRTR2 | |
| SCHEMBL18538040 | 0.81 | HPGD (0.40) | GSK3BSPRPOLBHCRTR1HCRTR2 | |
| SCHEMBL18538049 | 0.79 | ALDH1A1 (0.42) | GSK3BPOLBCYP1A2 | |
| SCHEMBL4409862 | 0.78 | SPR (0.50) | GSK3BSPRPOLB | |
| SCHEMBL25091063 | 0.77 | HCRTR1 (0.38) | GSK3BHCRTR1HCRTR2CYP1A2ATM | |
| SCHEMBL31457149 | 0.76 | ATM (0.53) | SPRATM | |
| SCHEMBL31457170 | 0.76 | ATM (0.44) | POLBATM | |
| SCHEMBL12031687 | 0.75 | GSK3B (0.59) | GSK3BSPRPOLB | |
| SCHEMBL29582154 | 0.74 | PI4KA (0.36) | GSK3BHCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240228484-A1 | MONOACYLGLYCEROL LIPASE MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2024-07-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240228484-A1 | MONOACYLGLYCEROL LIPASE MODULATORS | MGLL, LPL, PNLIP | GSK3B 581/4885SPR 3510/4885POLB 492/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.