Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 8/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | IKBKB | O14920 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2511949 | 0.87 | TP53 (0.41) | TP53HSD17B10MEN1KMT2A | |
| SCHEMBL2511075 | 0.82 | MEN1 (0.39) | DHFRTP53HSD17B10TDP1ALDH1A1 | |
| SCHEMBL2517588 | 0.81 | TARBP2 (0.36) | DHFRTP53HSD17B10ALDH1A1HTT | |
| SCHEMBL2512534 | 0.81 | KMT2A (0.36) | DHFRTP53HSD17B10ALDH1A1HTT | |
| SCHEMBL621374 | 0.81 | TP53 (0.43) | TP53HSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL2514017 | 0.81 | TP53 (0.37) | DHFRTP53HSD17B10ALDH1A1HTT | |
| SCHEMBL2516707 | 0.81 | KMT2A (0.35) | DHFRTP53HSD17B10ALDH1A1HTT | |
| SCHEMBL2513020 | 0.79 | TP53 (0.36) | DHFRTP53HSD17B10ALDH1A1HTT | |
| SCHEMBL2517605 | 0.79 | NUDT1 (0.39) | DHFRTP53HSD17B10ALDH1A1HTT | |
| SCHEMBL2514616 | 0.78 | MAP4K4 (0.36) | TP53HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8592592-B2 | Sweet flavor modifier | SENOMYX, INC. (US) | 2013-11-26 | — | — | US | disclosed |
| US-20110245353-A1 | SWEET FLAVOR MODIFIER | SENOMYS, INC. (US) | 2011-10-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110245353-A1 | SWEET FLAVOR MODIFIER | TAS2R5, TAS2R10, TAS2R50 | DHFR 2674/4885TP53 2533/4885HSD17B10 1094/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.