Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.35 |
| ▸ | FGFR3 | P22607 | 5/20 | 0.33 |
| ▸ | HTT | P42858 | 3/20 | 0.32 |
| ▸ | ABL1 | P00519 | 4/20 | 0.32 |
| ▸ | PTK6 | Q13882 | 2/20 | 0.32 |
| ▸ | LCK | P06239 | 1/20 | 0.32 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
| ▸ | KIF18A | Q8NI77 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25096804 | 0.94 | IRAK4 (0.35) | IRAK4FGFR3HTTABL1PTK6 | |
| SCHEMBL25096360 | 0.94 | ROCK2 (0.36) | IRAK4FGFR3HTTABL1PTK6 | |
| SCHEMBL30217685 | 0.94 | ROCK2 (0.36) | IRAK4FGFR3HTTABL1PTK6 | |
| SCHEMBL25096797 | 0.93 | IRAK4 (0.37) | IRAK4FGFR3HTTABL1PTK6 | |
| SCHEMBL25096907 | 0.92 | LCK (0.34) | IRAK4FGFR3ABL1PTK6LCK | |
| SCHEMBL25096535 | 0.91 | ROCK1 (0.35) | IRAK4FGFR3PTK6LCKAURKB | |
| SCHEMBL25097072 | 0.89 | FGFR3 (0.40) | IRAK4FGFR3HTTPTK6LCK | |
| SCHEMBL30217847 | 0.89 | FGFR3 (0.40) | IRAK4FGFR3HTTPTK6LCK | |
| SCHEMBL25096582 | 0.86 | KIF18A (0.35) | IRAK4FGFR3KIF18A | |
| SCHEMBL30217730 | 0.86 | KIF18A (0.35) | IRAK4FGFR3KIF18A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023034811-A1 | COMPOUNDS AND METHODS FOR MODULATING SPLICING | REMIX THERAPEUTICS INC. (US) | 2023-03-09 | — | — | WO | disclosed |