Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 2/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.36 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 4/20 | 0.35 |
| ▸ | FGFR3 | P22607 | 3/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.34 |
| ▸ | WEE1 | P30291 | 1/20 | 0.33 |
| ▸ | PLK1 | P53350 | 1/20 | 0.33 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.33 |
| ▸ | KIF18A | Q8NI77 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25096360 | 1.00 | ROCK2 (0.36) | ROCK2LCKPTK6AURKBABL1 | |
| SCHEMBL25096907 | 0.97 | LCK (0.34) | ROCK2LCKPTK6AURKBABL1 | |
| SCHEMBL25096535 | 0.95 | ROCK1 (0.35) | LCKPTK6AURKBFGFR3IRAK4 | |
| SCHEMBL25096797 | 0.95 | IRAK4 (0.37) | ROCK2LCKPTK6AURKBABL1 | |
| SCHEMBL25096800 | 0.94 | IRAK4 (0.35) | ROCK2LCKPTK6AURKBABL1 | |
| SCHEMBL25096804 | 0.93 | IRAK4 (0.35) | ROCK2LCKPTK6AURKBABL1 | |
| SCHEMBL25097072 | 0.92 | FGFR3 (0.40) | LCKPTK6AURKBFGFR3IRAK4 | |
| SCHEMBL30217847 | 0.92 | FGFR3 (0.40) | LCKPTK6AURKBFGFR3IRAK4 | |
| SCHEMBL25096536 | 0.91 | KDM4E (0.36) | ROCK2LCKPTK6AURKBABL1 | |
| SCHEMBL25096582 | 0.91 | KIF18A (0.35) | FGFR3IRAK4SCN10AKIF18A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4395891-A1 | COMPOUNDS AND METHODS FOR MODULATING SPLICING | Remix Therapeutics Inc. (US) | 2024-07-10 | — | — | EP | disclosed |
| CN-118234724-A | Compounds and methods for modulating splicing | 雷密克斯医疗公司 | 2024-06-21 | — | — | CN | disclosed |
| WO-2023034811-A1 | COMPOUNDS AND METHODS FOR MODULATING SPLICING | REMIX THERAPEUTICS INC. (US) | 2023-03-09 | — | — | WO | disclosed |