Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATIC | P31939 | 2/20 | 0.46 |
| ▸ | FBP1 | P09467 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.42 |
| ▸ | TYMP | P19971 | 3/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20099214 | 0.84 | KDM4E (0.64) | ATICFBP1KDM4ETDP1TP53 | |
| SCHEMBL17792206 | 0.84 | KDM4E (0.64) | ATICFBP1KDM4ETDP1TP53 | |
| SCHEMBL15698100 | 0.84 | KDM4E (0.64) | ATICFBP1KDM4ETDP1TP53 | |
| SCHEMBL15700258 | 0.84 | KDM4E (0.64) | ATICFBP1KDM4ETDP1TP53 | |
| SCHEMBL8718284 | 0.84 | KDM4E (0.64) | ATICFBP1KDM4ETDP1TP53 | |
| SCHEMBL850150 | 0.83 | FBP1 (0.49) | ATICFBP1KDM4ETDP1TP53 | |
| SCHEMBL22567113 | 0.83 | ATIC (0.69) | ATICFBP1KDM4ETDP1TP53 | |
| SCHEMBL22459604 | 0.83 | ATIC (0.69) | ATICFBP1KDM4ETDP1TP53 | |
| SCHEMBL21110493 | 0.83 | ATIC (0.69) | ATICFBP1KDM4ETDP1TP53 | |
| SCHEMBL73326 | 0.83 | ATIC (0.69) | ATICFBP1KDM4ETDP1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2564194-B1 | METABOLIC BIOMARKERS OF AUTISM | WISCONSIN ALUMNI RES FOUND (US) | 2019-07-10 | — | — | EP | claimed |
| US-20120190055-A1 | MOLECULE BIOMARKERS OF AUTISM | STEMINA BIOMARKER DISCOVERY, INC. (US) | 2012-07-26 | — | — | US | claimed |
| EP-2564194-B1 | METABOLIC BIOMARKERS OF AUTISM | WISCONSIN ALUMNI RES FOUND (US) | 2019-07-10 | — | — | EP | disclosed |
| US-10330688-B2 | Metabolic biomarkers of autism | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2019-06-25 | — | — | US | disclosed |
| US-20170192019-A1 | Metabolic Biomarkers of Autism | WISCONSIN ALUMNI RES FOUND (US) | 2017-07-06 | — | — | US | disclosed |
| EP-2401696-B1 | MAMMALIAN CELL LINE MODELS AND RELATED METHODS | INTREXON CEU INC (US) | 2017-06-21 | — | — | EP | disclosed |
| US-9547013-B2 | Molecule biomarkers of autism | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2017-01-17 | — | — | US | disclosed |
| US-20140309186-A1 | Metabolomics-Based Identification of Disease-Causing Agents | GEORGIA TECH RESEARCH CORPORATION | 2014-10-16 | — | — | US | disclosed |
| US-8494779-B2 | Method for screening essential metabolites in growth of microorganisms | KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2013-07-23 | — | — | US | disclosed |
| US-20120190055-A1 | MOLECULE BIOMARKERS OF AUTISM | STEMINA BIOMARKER DISCOVERY, INC. (US) | 2012-07-26 | — | — | US | disclosed |
| US-20120191434-A1 | ARTICLES OF MANUFACTURE AND METHODS FOR MODELING CHINESE HAMSTER OVARY (CHO) CELL METABOLISM | GT LIFE SCIENCES, INC. (US) | 2012-07-26 | — | — | US | disclosed |
| US-20110246081-A1 | Metabolomics-Based Identification of Disease-Causing Agents | GEORGIA TECH RESEARCH CORPORATION (US) | 2011-10-06 | — | — | US | disclosed |
| US-20100143911-A1 | METHOD FOR SCREENING ESSENTIAL METABOLITES IN GROWTH OF MICROORGANISMS | KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2010-06-10 | — | — | US | disclosed |