SCHEMBL850150

SCHEMBL850150

Nc1c(C(=O)O)ncn1C1O[C@H](C(O)P(=O)(O)O)[C@@H](O)[C@H]1O

nearest known ligand 0.49

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
FBP1 P09467 1/20 0.49
ATIC P31939 1/20 0.49
KDM4E B2RXH2 2/20 0.47
TDP1 Q9NUW8 1/20 0.47
TP53 P04637 1/20 0.47
MAPT P10636 1/20 0.47
TYMP P19971 3/20 0.40
ALDH1A1 P00352 1/20 0.37
GAA P10253 1/20 0.37
HTT P42858 1/20 0.37
BLM P54132 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
TSHR P16473 1/20 0.37
PRMT5 O14744 4/20 0.37
WDR77 Q9BQA1 3/20 0.37
NT5E P21589 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL938225 0.91 ATIC (0.60) FBP1ATICKDM4ETDP1TP53
SCHEMBL2509891 0.83 ATIC (0.46) FBP1ATICKDM4ETDP1TP53
SCHEMBL28773388 0.81 ATIC (0.47) FBP1ATICKDM4ETDP1TP53
SCHEMBL28861552 0.78 NT5E (0.38) FBP1ATICKDM4ETDP1TP53
SCHEMBL2510748 0.77 NT5E (0.39) FBP1ATICPRMT5WDR77NT5E
SCHEMBL29152304 0.76 ATIC (0.47) FBP1ATICKDM4ETDP1TP53
SCHEMBL940486 0.76 ATIC (0.64) FBP1ATICKDM4ETDP1TP53
SCHEMBL188236 0.76 NT5E (0.41) FBP1ATICSMN1; SMN2PRMT5WDR77
SCHEMBL19814010 0.76 NT5E (0.41) FBP1ATICSMN1; SMN2PRMT5WDR77
SCHEMBL4366540 0.75 ATIC (0.84) FBP1ATICKDM4ETDP1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100143911-A1 METHOD FOR SCREENING ESSENTIAL METABOLITES IN GROWTH OF MICROORGANISMS KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2010-06-10 US claimed
EP-2097743-A1 METHOD FOR SCREENING ESSENTIAL METABOLITES IN GROWTH OF MICROORGANISMS Korea Advanced Institute of Science and Technology (KR) 2009-09-09 EP claimed
WO-2008078911-A1 METHOD FOR SCREENING ESSENTIAL METABOLITES IN GROWTH OF MICROORGANISMS KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2008-07-03 WO claimed
US-20240018559-A1 GENETICALLY ENGINEERED BACTERIUM CAPABLE OF PRODUCING CYTOKININS WITH ISOPRENOID SIDE CHAINS ACIES BIO D.O.O. (SI) 2024-01-18 US disclosed
CN-116832017-A Application of cinnamaldehyde 中国科学院昆明动物研究所 2023-10-03 CN disclosed
EP-4006139-A1 GENETICALLY ENGINEERED BACTERIUM CAPABLE OF PRODUCING CYTOKININS WITH ISOPRENOID SIDE CHAINS Acies Bio d.o.o. (SI) 2022-06-01 EP disclosed
WO-2022095809-A1 NEW APPLICATION OF COMPOUNDS INFLUENCING SAICAR EXPRESSION 广州君赫生物科技有限公司 2022-05-12 WO disclosed
CN-113603721-A Method for synthesizing SAICAR 重庆文理学院 2021-11-05 CN disclosed
EP-2463654-B1 Compositions and methods for modeling saccharomyces cerevisiae metabolism UNIV CALIFORNIA (US) 2020-06-03 EP disclosed
EP-2401696-B1 MAMMALIAN CELL LINE MODELS AND RELATED METHODS INTREXON CEU INC (US) 2017-06-21 EP disclosed
US-20140309186-A1 Metabolomics-Based Identification of Disease-Causing Agents GEORGIA TECH RESEARCH CORPORATION 2014-10-16 US disclosed
EP-2097743-A1 METHOD FOR SCREENING ESSENTIAL METABOLITES IN GROWTH OF MICROORGANISMS Korea Advanced Institute of Science and Technology (KR) 2009-09-09 EP disclosed
US-7585617-B2 For liberating and isolating component materials contained in a biological cell and for qualitative detection and quantitative determination of the liberated materials INSILICO BIOTECHNOLOGY GMBH (DE) 2009-09-08 US disclosed
WO-2009052186-A1 METABOLOMICS-BASED IDENTIFICATION OF DISEASE-CAUSING AGENTS GEORGIA TECH RESEARCH CORPORATION (US) 2009-04-23 WO disclosed
WO-2008078911-A1 METHOD FOR SCREENING ESSENTIAL METABOLITES IN GROWTH OF MICROORGANISMS KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2008-07-03 WO disclosed
EP-1887081-A2 DNA Sequences Ceres Incorporated (US) 2008-02-13 EP disclosed
US-20070298484-A1 Method and Device for Thermal Conditioning of a Cell INSILICO BIOTECHNOLOGY GMBH (DE) 2007-12-27 US disclosed
EP-1586645-A2 Sequence-determined DNA fragments and corresponding polypeptides encoded thereby Ceres Incorporated (US) 2005-10-19 EP disclosed
EP-1059354-A2 Sequence-determined DNA fragments and corresponding polypeptides encoded thereby Ceres Incorporated (US) 2000-12-13 EP disclosed
EP-1033405-A2 Sequence-determined DNA fragments and corresponding polypeptides encoded thereby Ceres Incorporated (US) 2000-09-06 EP disclosed