Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 1/20 | 0.57 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | CHRM1 | P11229 | 8/20 | 0.52 |
| ▸ | CHRM3 | P20309 | 8/20 | 0.52 |
| ▸ | CHRM2 | P08172 | 7/20 | 0.52 |
| ▸ | CHRM4 | P08173 | 7/20 | 0.52 |
| ▸ | CHRM5 | P08912 | 6/20 | 0.52 |
| ▸ | CHRNB2 | P17787 | 4/20 | 0.52 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.52 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.52 |
| ▸ | HTR1A | P08908 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | PGR | P06401 | 1/20 | 0.52 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.52 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.52 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.52 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25099001 | 0.84 | ADRA2A (0.63) | ADRA2AADRA1AMAPTBLMCYP2C19 | |
| SCHEMBL16353073 | 0.83 | ADRA2A (0.73) | ADRA2AADRA1AMAPTBLMCYP2C19 | |
| SCHEMBL29309550 | 0.82 | ADRA2A (0.73) | ADRA2AADRA1AMAPTBLMCYP2C19 | |
| SCHEMBL15438002 | 0.79 | MGAM (0.41) | CHRM1MAPK1LMNATSHRGAA | |
| SCHEMBL6001765 | 0.79 | CHRM1 (0.60) | ADRA2AADRA1AMAPTBLMCYP2C19 | |
| SCHEMBL12535776 | 0.78 | TSHR (0.37) | ADRA2AADRA1ASMN1; SMN2TSHRGAA | |
| SCHEMBL27643498 | 0.78 | ALDH1A1 (0.36) | ADRA2AADRA1AMAPTLMNAGAA | |
| SCHEMBL14045415 | 0.77 | CHRM1 (0.64) | ADRA2AADRA1AMAPTBLMCYP2C19 | |
| SCHEMBL780253 | 0.77 | ADRA2A (0.64) | ADRA2AADRA1AMAPTBLMCYP2C19 | |
| Hydrochloric Acid SCHEMBL28778365 | 0.77 | CHRM1 (0.61) | ADRA2AADRA1AMAPTBLMCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12037354-B2 | Cyclic pantetheine derivatives and uses thereof | VECTIVBIO COMET AG (CH) | 2024-07-16 | — | — | US | disclosed |
| US-20230072313-A1 | CYCLIC PANTETHEINE DERIVATIVES AND USES THEREOF | VECTIVBIO COMET AG, F/K/A COMET THERAPEUTICS, INC. (CH) | 2023-03-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230072313-A1 | CYCLIC PANTETHEINE DERIVATIVES AND USES THEREOF | VNN1, VKORC1, PANK3 | ADRA2A 4101/4885ADRA1A 4091/4885MAPT 4082/4885 |
| US-12037354-B2 | Cyclic pantetheine derivatives and uses thereof | VNN1, VKORC1, PANK3 | ADRA2A 4101/4885ADRA1A 4091/4885MAPT 4082/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.