SCHEMBL2510085

SCHEMBL2510085

O=C(O)C(=O)[C@H](O)COP(=O)(O)O

nearest known ligand 0.69

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
PGK1 P00558 1/20 0.69
PGK2 P07205 1/20 0.69
PGD P52209 4/20 0.53
MPI P34949 1/20 0.44
ENPP2 Q13822 3/20 0.37
LPAR5 Q9H1C0 2/20 0.37
LPAR6 P43657 1/20 0.37
LPAR1 Q92633 1/20 0.37
LPAR4 Q99677 1/20 0.37
LPAR2 Q9HBW0 1/20 0.37
LPAR3 Q9UBY5 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21724798 1.00 PGK1 (0.69) PGK1PGK2PGDMPIENPP2
3-Phosphoglyceric Acid SCHEMBL27483 0.82 PGK1 (1.00) PGK1PGK2PGDMPIENPP2
3-Phosphoglyceric Acid SCHEMBL27482 0.82 PGK1 (1.00) PGK1PGK2PGDMPIENPP2
3-Phosphoglyceric Acid SCHEMBL30428419 0.82 PGK1 (1.00) PGK1PGK2PGDMPIENPP2
3-Phosphoglyceric Acid SCHEMBL2497743 0.82 PGK1 (1.00) PGK1PGK2PGDMPIENPP2
SCHEMBL16449212 0.81 PGK1 (0.61) PGK1PGK2PGDMPIENPP2
SCHEMBL30606836 0.81 PGK1 (0.61) PGK1PGK2PGDMPIENPP2
SCHEMBL13967818 0.79 PGK1 (0.59) PGK1PGK2PGDMPIENPP2
SCHEMBL7538927 0.79 PGD (0.71) PGK1PGK2PGDMPIENPP2
SCHEMBL11860852 0.78 PGK1 (0.57) PGK1PGK2PGDMPIENPP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140309186-A1 Metabolomics-Based Identification of Disease-Causing Agents GEORGIA TECH RESEARCH CORPORATION 2014-10-16 US disclosed
US-20110246081-A1 Metabolomics-Based Identification of Disease-Causing Agents GEORGIA TECH RESEARCH CORPORATION (US) 2011-10-06 US disclosed
WO-2009052186-A1 METABOLOMICS-BASED IDENTIFICATION OF DISEASE-CAUSING AGENTS GEORGIA TECH RESEARCH CORPORATION (US) 2009-04-23 WO disclosed