3-Phosphoglyceric Acid

3-Phosphoglyceric Acid

SCHEMBL2497743

O=C(O)[C@H](O)COP(=O)(O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
PGK1 P00558 1/20 1.00
PGK2 P07205 1/20 1.00
PGD P52209 3/20 0.63
MPI P34949 1/20 0.47
OR51E2 Q9H255 1/20 0.40
LPAR5 Q9H1C0 2/20 0.39
LPAR6 P43657 1/20 0.39
LPAR1 Q92633 1/20 0.39
LPAR4 Q99677 1/20 0.39
LPAR2 Q9HBW0 1/20 0.39
LPAR3 Q9UBY5 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
ENPP2 Q13822 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
3-Phosphoglyceric Acid SCHEMBL30428419 1.00 PGK1 (1.00) PGK1PGK2PGDMPIOR51E2
3-Phosphoglyceric Acid SCHEMBL27483 1.00 PGK1 (1.00) PGK1PGK2PGDMPIOR51E2
3-Phosphoglyceric Acid SCHEMBL27482 1.00 PGK1 (1.00) PGK1PGK2PGDMPIOR51E2
3-Phosphoglyceric Acid SCHEMBL8006738 0.90 PGK1 (0.81) PGK1PGK2PGDMPISMN1; SMN2
SCHEMBL1812894 0.83 PGK1 (0.70) PGK1PGK2PGDLPAR1LPAR3
SCHEMBL21724798 0.82 PGK1 (0.69) PGK1PGK2PGDMPILPAR5
SCHEMBL2510085 0.82 PGK1 (0.69) PGK1PGK2PGDMPILPAR5
SCHEMBL29357297 0.81 PGK1 (0.68) PGK1PGK2PGDMPILPAR5
3-Phosphoglyceric Acid SCHEMBL15019970 0.80 PGK1 (0.64) PGK1PGK2PGD
SCHEMBL704407 0.79 PGK1 (0.65) PGK1PGK2PGDMPILPAR5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 350 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260063623-A1 METHODS OF ASSESSING METABOLIC FLUX UNIV MICHIGAN REGENTS (US) 2026-03-05 US claimed
US-20260035705-A1 ENGINEERED MICROORGANISMS WITH G3P ->3PG ENZYME AND/OR FRUCTOSE-1,6-BISPHOSPHATASE INCLUDING THOSE HAVING SYNTHETIC OR ENHANCED METHYLOTROPHY AGAIN BIO APS (DK) 2026-02-05 US claimed
EP-4602365-A2 METHODS OF ASSESSING METABOLIC FLUX The Regents of The University of Michigan (US) 2025-08-20 EP claimed
EP-4537111-A2 MULTI-OMICS ASSESSMENT Prognomiq Inc (US) 2025-04-16 EP claimed
WO-2025072741-A1 PRESERVATIVES FOR MOLECULAR SAMPLE ANALYSIS WITH SAMPLE COLLECTION DEVICES BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2025-04-03 WO claimed
US-12234463-B2 Engineered microorganisms with G3P → 3PG enzyme and/or fructose-1,6-bisphosphatase including those having synthetic or enhanced methylotrophy GENOMATICA, INC. (US) 2025-02-25 US claimed
WO-2025016307-A1 HEALTH HOMEOSTASIS MODEL, ELASTIC HOMEOSTASIS MODEL, AND USAGE METHOD THEREFOR 汤臣倍健股份有限公司 2025-01-23 WO claimed
EP-4457513-A1 COMPOSITIONS AND METHODS FOR DIAGNOSING AND TREATING CHRONIC KIDNEY DISEASE Société des Produits Nestlé S.A. (CH) 2024-11-06 EP claimed
WO-2024206366-A2 GENETICALLY ENCODED SYSTEM FOR QUANTIFYING RUBISCO ACTIVITY IN CATALYZING CARBON FIXATION THE SCRIPPS RESEARCH INSTITUTE (US) 2024-10-03 WO claimed
EP-4437319-A1 METHODS AND COMPOSITIONS FOR ANALYTE QUANTIFICATION Matterworks Inc (US) 2024-10-02 EP claimed
EP-4141122-A2 CARBON-NEUTRAL AND CARBON-POSITIVE PHOTORESPIRATION BYPASS ROUTES SUPPORTING HIGHER PHOTOSYNTHETIC RATE AND YIELD Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2023-03-01 EP claimed
WO-2023015285-A1 MICROORGANISMS AND METHODS FOR IMPROVED BIOLOGICAL PRODUCTION OF ETHYLENE GLYCOL LANZATECH, INC. (US) 2023-02-09 WO claimed
US-20230015215-A1 EVALUATION METHOD OF DIFFERENTIATION STATE OF CELLS, AND CELL CULTURE SYSTEM HITACHI HIGH-TECH CORPORATION (JP) 2023-01-19 US claimed
EP-4092129-A1 EVALUATION METHOD OF DIFFERENTIATION STATE OF CELLS, AND CELL CULTURE SYSTEM Hitachi High-Tech Corporation (JP) 2022-11-23 EP claimed
US-20220348897-A1 GENETICALLY OPTIMISED MICROORGANISM FOR PRODUCING MOLECULES OF INTEREST EPPEN EUROPE (FR) 2022-11-03 US claimed
CN-114846151-A Method for evaluating cell differentiation state and cell culture system 株式会社日立高新技术 2022-08-02 CN claimed
US-20220177895-A1 ENGINEERED MICROORGANISMS WITH G3P -> 3PG ENZYME AND/OR FRUCTOSE-1,6-BISPHOSPHATASE INCLUDING THOSE HAVING SYNTHETIC OR ENHANCED METHYLOTROPHY AGAIN BIO APS (DK) 2022-06-09 US claimed
EP-3946054-A1 COMPOSITIONS, METHODS AND SYSTEMS FOR PROTEIN CORONA ANALYSIS FROM BIOFLUIDS AND USES THEREOF Seer, Inc. (US) 2022-02-09 EP claimed
US-20160282351-A1 SALIVARY BIOMARKERS FOR CANCERS, METHODS AND DEVICES FOR ASSAYING THE SAME, AND METHODS FOR DETERMINING SALIVARY BIOMARKERS FOR CANCERS SALIVATECH CO., LTD. (JP) 2016-09-29 US claimed
EP-3064940-A1 SALIVARY BIOMARKER FOR CANCER, METHOD AND DEVICE FOR ASSAYING SAME, AND METHOD FOR DETERMINING SALIVARY BIOMARKER FOR CANCER Salivatech Co., Ltd. (JP) 2016-09-07 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260063623-A1 METHODS OF ASSESSING METABOLIC FLUX PC, SLC2A1, SLC2A4 PGK1 199/4885PGK2 329/4885PGD 19/4885
US-20260035705-A1 ENGINEERED MICROORGANISMS WITH G3P ->3PG ENZYME AND/OR FRUCTOSE-1,6-BISPHOSPHATASE INCLUDING THOSE HAVING SYNTHETIC OR ENHANCED METHYLOTROPHY ME1, FBP1, ME3 PGK1 44/4885PGK2 75/4885PGD 10/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.