Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | BLM | P54132 | 1/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.44 |
| ▸ | AOC1 | P19801 | 2/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.42 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.39 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.36 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.35 |
| ▸ | TLK2 | Q86UE8 | 2/20 | 0.35 |
| ▸ | JAK3 | P52333 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19176562 | 0.79 | CYP3A4 (0.54) | KDM4EBLMNPSR1CYP3A4TSHR | |
| Cis-Urocanic Acid SCHEMBL12963908 | 0.78 | CYP3A4 (1.00) | KDM4EBLMNPSR1CYP3A4TSHR | |
| Cis-Urocanic Acid SCHEMBL1136889 | 0.78 | CYP3A4 (1.00) | KDM4EBLMNPSR1CYP3A4TSHR | |
| Cis-Urocanic Acid SCHEMBL338885 | 0.78 | CYP3A4 (1.00) | KDM4EBLMNPSR1CYP3A4TSHR | |
| SCHEMBL15668642 | 0.77 | CYP3A4 (0.70) | KDM4EBLMNPSR1CYP3A4TSHR | |
| SCHEMBL23749602 | 0.77 | CYP3A4 (0.70) | KDM4EBLMNPSR1CYP3A4TSHR | |
| SCHEMBL21334959 | 0.76 | KMT2A (1.00) | KDM4EBLMNPSR1CYP3A4TSHR | |
| SCHEMBL8552929 | 0.76 | KMT2A (1.00) | KDM4EBLMNPSR1CYP3A4TSHR | |
| SCHEMBL2567149 | 0.72 | MEN1 (0.69) | KDM4EBLMNPSR1CYP3A4TSHR | |
| SCHEMBL13895761 | 0.72 | CYP3A4 (0.58) | KDM4EBLMNPSR1CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023028350-A1 | THERAPEUTIC COMPOSITIONS AND RELATED METHODS | BOYCE THOMPSON INSTITUTE FOR PLANT RESEARCH, INC. (US) | 2023-03-02 | — | — | WO | disclosed |