Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 1.00 |
| ▸ | MEN1 | O00255 | 2/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.64 |
| ▸ | BLM | P54132 | 1/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.44 |
| ▸ | AOC1 | P19801 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | TYR | P14679 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21334959 | 1.00 | KMT2A (1.00) | KMT2AMEN1KDM4EBLMNPSR1 | |
| SCHEMBL11598556 | 0.82 | MEN1 (0.69) | KMT2AMEN1KDM4EBLMNPSR1 | |
| SCHEMBL2567149 | 0.82 | MEN1 (0.69) | KMT2AMEN1KDM4EBLMNPSR1 | |
| Cis-Urocanic Acid SCHEMBL338885 | 0.78 | CYP3A4 (1.00) | KMT2AMEN1KDM4EBLMNPSR1 | |
| Cis-Urocanic Acid SCHEMBL1136889 | 0.78 | CYP3A4 (1.00) | KMT2AMEN1KDM4EBLMNPSR1 | |
| Cis-Urocanic Acid SCHEMBL12963908 | 0.78 | CYP3A4 (1.00) | KMT2AMEN1KDM4EBLMNPSR1 | |
| SCHEMBL23749602 | 0.77 | CYP3A4 (0.70) | KMT2AMEN1KDM4EBLMNPSR1 | |
| SCHEMBL15668642 | 0.77 | CYP3A4 (0.70) | KMT2AMEN1KDM4EBLMNPSR1 | |
| SCHEMBL25101013 | 0.76 | KDM4E (0.64) | KMT2AMEN1KDM4EBLMNPSR1 | |
| SCHEMBL22392209 | 0.74 | MEN1 (0.58) | KMT2AMEN1KDM4EBLMNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0858457-A1 | 5-MEMBERED HETEROCYCLES, PHARMACEUTICAL AGENTS CONTAINING SAID COMPOUNDS AND THE USE THEREOF AND METHODS OF PRODUCING THEM | Dr. Karl Thomae GmbH (DE) | 1998-08-19 | — | — | EP | disclosed |
| WO-1997015567-A1 | 5-MEMBERED HETEROCYCLES, PHARMACEUTICAL AGENTS CONTAINING SAID COMPOUNDS AND THE USE THEREOF AND METHODS OF PRODUCING THEM | DR. KARL THOMAE GMBH (DE) | 1997-05-01 | — | — | WO | disclosed |