Cis-Urocanic Acid

Cis-Urocanic Acid

SCHEMBL338885

O=C(O)/C=C/c1cnc[nH]1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 1.00
TSHR P16473 2/20 1.00
KDM4E B2RXH2 2/20 1.00
BLM P54132 1/20 1.00
NPSR1 Q6W5P4 1/20 1.00
MEN1 O00255 1/20 0.64
KMT2A Q03164 1/20 0.64
AOC1 P19801 2/20 0.48
PADI4 Q9UM07 1/20 0.45
SMYD3 Q9H7B4 1/20 0.45
ALDH1A1 P00352 2/20 0.41
GABRA1 P14867 1/20 0.41
NFKB1 P19838 1/20 0.41
GABRR1 P24046 1/20 0.41
GABRR2 P28476 1/20 0.41
GABRA5 P31644 1/20 0.41
GABRB2 P47870 1/20 0.41
GABRA4 P48169 1/20 0.41
MAPT P10636 1/20 0.40
PMP22 Q01453 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cis-Urocanic Acid SCHEMBL1136889 1.00 CYP3A4 (1.00) CYP3A4TSHRKDM4EBLMNPSR1
Cis-Urocanic Acid SCHEMBL12963908 1.00 CYP3A4 (1.00) CYP3A4TSHRKDM4EBLMNPSR1
SCHEMBL15668642 0.82 CYP3A4 (0.70) CYP3A4TSHRKDM4EBLMNPSR1
SCHEMBL23749602 0.82 CYP3A4 (0.70) CYP3A4TSHRKDM4EBLMNPSR1
SCHEMBL8086657 0.79
SCHEMBL8552929 0.78 KMT2A (1.00) CYP3A4TSHRKDM4EBLMNPSR1
SCHEMBL21334959 0.78 KMT2A (1.00) CYP3A4TSHRKDM4EBLMNPSR1
SCHEMBL25101013 0.78 KDM4E (0.64) CYP3A4TSHRKDM4EBLMNPSR1
SCHEMBL2567149 0.74 MEN1 (0.69) CYP3A4TSHRKDM4EBLMNPSR1
SCHEMBL11598554 0.74 MEN1 (0.69) CYP3A4TSHRKDM4EBLMNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 519 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260091067-A1 METHODS AND USES OF MICROBIOME COMPOSITIONS, COMPONENTS, OR METABOLITES FOR TREATING INSULIN-ASSOCIATED DISEASES MARVELBIOME INC (US) 2026-04-02 US claimed
US-12584924-B2 Compositions and methods for diagnosing and treating chronic kidney disease SOCIETE DES PRODUITS NESTLE S.A. (CH) 2026-03-24 US claimed
EP-3976811-B1 METABOLOMIC CHARACTERIZATION OF MICROORGANISMS LEWIS IAN ANDREW (CA) 2026-02-11 EP claimed
EP-4587116-A2 METHODS AND USES OF MICROBIOME COMPOSITIONS, COMPONENTS, OR METABOLITES FOR TREATING INSULIN-ASSOCIATED DISEASES MarvelBiome, Inc. (US) 2025-07-23 EP claimed
WO-2025054048-A1 METHODS AND USES OF MICROBIOME COMPOSITIONS, COMPONENTS, OR METABOLITES FOR TREATING LIPID AND CHOLESTEROL METABOLISM ASSOCIATED DISEASES, DISORDERS, AND CONDITIONS MarvelBiome, Inc. (US) 2025-03-13 WO claimed
EP-4457513-A1 COMPOSITIONS AND METHODS FOR DIAGNOSING AND TREATING CHRONIC KIDNEY DISEASE Société des Produits Nestlé S.A. (CH) 2024-11-06 EP claimed
EP-4452259-A1 COMPOSITIONS COMPRISING UROLITHIN FOR TREATING MUSCLE DECLINE AND A KIDNEY DYSFUNCTION Société des Produits Nestlé S.A. (CH) 2024-10-30 EP claimed
EP-4440342-A1 METHODS AND USES OF MICROBIOME COMPOSITIONS, COMPONENTS, OR METABOLITES FOR TREATING VAGUS NERVE ASSOCIATED DISEASES, DISORDERS, AND CONDITIONS MarvelBiome, Inc. (US) 2024-10-09 EP claimed
CN-118714936-A Methods and uses of microbial compositions, components or metabolites for the treatment of vagal nerve related diseases, disorders and conditions 奇迹生物公司 2024-09-27 CN claimed
CN-118425363-A Method for simultaneously measuring trans-urocanic acid, cis-urocanic acid, histidine and histamine in fish products 江苏科技大学 2024-08-02 CN claimed
WO-2023102149-A1 METHODS AND USES OF MICROBIOME COMPOSITIONS, COMPONENTS, OR METABOLITES FOR TREATING VAGUS NERVE ASSOCIATED DISEASES, DISORDERS, AND CONDITIONS MarvelBiome, Inc. (US) 2023-06-08 WO claimed
CN-116003710-A Polyacrylic polymer modified substrate, preparation method thereof and application thereof in preparation of biochip 中国海洋大学 2023-04-25 CN claimed
WO-2023044076-A1 METHODS AND USES OF MICROBIOME COMPOSITIONS, COMPONENTS, OR METABOLITES FOR TREATING NEURODEGENERATIVE DISEASES MarvelBiome, Inc. (US) 2023-03-23 WO claimed
US-20230087305-A1 METHODS AND USES OF MICROBIOME COMPOSITIONS, COMPONENTS, OR METABOLITES FOR TREATING NEURODEGENERATIVE DISEASES MarvelBiome, Inc. 2023-03-23 US claimed
WO-2022192755-A1 METHODS AND USES OF MICROBIOME COMPOSITIONS, COMPONENTS, OR METABOLITES FOR TREATING EYE DISORDERS MarvelBiome, Inc. (US) 2022-09-15 WO claimed
US-20220082554-A1 Prediction and/or Determination Marker for Effectiveness of Treatment with Drug Containing PD-1 Signal Inhibitor KYOTO UNIVERSITY (JP) 2022-03-17 US claimed
EP-1060223-B1 PHOTOCHROMIC COATING COMPOUND AND SUBSTRATE COATED WITH SAME INST NEUE MAT GEMEIN GMBH (DE) 2004-08-18 EP claimed
US-6639039-B1 Polysiloxane precondensate having curable glycidol or methacryl functionality, dye, stabilizer and particles; light and scratch resistance Institut für Neue Materialien Gemeinnützige GmbH (DE) 2003-10-28 US claimed
EP-1060223-A1 PHOTOCHROMIC COATING COMPOUND AND SUBSTRATE COATED WITH SAME Institut Für Neue Materialien gem. GmbH (DE) 2000-12-20 EP claimed
WO-1999041326-A1 PHOTOCHROMIC COATING COMPOUND AND SUBSTRATE COATED WITH SAME INSTITUT FÜR NEUE MATERIALIEN GEM. GMBH (DE) 1999-08-19 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260091067-A1 METHODS AND USES OF MICROBIOME COMPOSITIONS, COMPONENTS, OR METABOLITES FOR TREATING INSULIN-ASSOCIATED DISEASES IAPP, GPR119, FAHD1 CYP3A4 1976/4885TSHR 1923/4885KDM4E 4749/4885
US-12584924-B2 Compositions and methods for diagnosing and treating chronic kidney disease GLS, AADAT, FGF23 CYP3A4 4804/4885TSHR 2407/4885KDM4E 124/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.