SCHEMBL2510169

SCHEMBL2510169

CCc1ccc2nc(C)c(C(=O)O)c(N)c2c1OCC(C)(C)NC(=O)CCOC

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 1/20 0.33
▸ KMT2A Q03164 1/20 0.33
▸ MAP4K4 O95819 3/20 0.30
▸ ACSS2 Q9NR19 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2509463 0.92 MEN1 (0.35) MEN1KMT2A
SCHEMBL2512542 0.91 MEN1 (0.34) MEN1KMT2A
SCHEMBL2511002 0.85 NPSR1 (0.38) MEN1KMT2AMAP4K4
SCHEMBL2514021 0.85 MAPT (0.40) KMT2A
SCHEMBL2510945 0.84 SMN1; SMN2 (0.35) MEN1KMT2A
SCHEMBL2516719 0.84 KMT2A (0.33) MEN1KMT2A
SCHEMBL2515079 0.84 TSHR (0.32) MEN1KMT2AMAP4K4
SCHEMBL2516707 0.84 KMT2A (0.35) MEN1KMT2A
SCHEMBL2510159 0.84 MEN1 (0.32) MEN1KMT2A
SCHEMBL620824 0.84 MEN1 (0.39) MEN1KMT2AMAP4K4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8592592-B2 Sweet flavor modifier SENOMYX, INC. (US) 2013-11-26 — — US disclosed
US-20110245353-A1 SWEET FLAVOR MODIFIER SENOMYS, INC. (US) 2011-10-06 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110245353-A1 SWEET FLAVOR MODIFIER TAS2R5, TAS2R10, TAS2R50 MEN1 784/4885KMT2A 1673/4885MAP4K4 3531/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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