Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | USP7 | Q93009 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | DHFR | P00374 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2511002 | 0.93 | NPSR1 (0.38) | NPSR1MEN1KMT2AMAP4K4LMNA | |
| SCHEMBL2511738 | 0.92 | MAP4K4 (0.32) | MEN1KMT2AMAP4K4DHFR | |
| SCHEMBL2510945 | 0.91 | SMN1; SMN2 (0.35) | NPSR1MEN1KMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL2512402 | 0.91 | DHFR (0.31) | TSHRNPSR1MEN1KMT2AMAP4K4 | |
| SCHEMBL2516719 | 0.91 | KMT2A (0.33) | NPSR1MEN1KMT2ASMN1; SMN2HTT | |
| SCHEMBL2509610 | 0.90 | MAP4K4 (0.36) | NPSR1MEN1KMT2AMAP4K4LMNA | |
| SCHEMBL2512460 | 0.88 | HSD17B1 (0.32) | MAP4K4 | |
| SCHEMBL2512762 | 0.88 | MAPT (0.33) | MEN1KMT2ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL2511915 | 0.88 | TLR7 (0.34) | MEN1KMT2ASMN1; SMN2LMNAHTT | |
| SCHEMBL2517583 | 0.87 | MAPT (0.38) | TSHRNPSR1MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8592592-B2 | Sweet flavor modifier | SENOMYX, INC. (US) | 2013-11-26 | — | — | US | disclosed |
| US-20110245353-A1 | SWEET FLAVOR MODIFIER | SENOMYS, INC. (US) | 2011-10-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110245353-A1 | SWEET FLAVOR MODIFIER | TAS2R5, TAS2R10, TAS2R50 | TSHR 2995/4885NPSR1 1367/4885MEN1 784/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.