Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | BAZ2B | Q9UIF8 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PLK1 | P53350 | 2/20 | 0.35 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 5/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13850421 | 0.82 | MAOA (0.45) | MAOAMAOBPARP1KDM4EALDH1A1 | |
| SCHEMBL19125590 | 0.81 | MAOA (0.42) | MAOAMAOBRAB9AGAANPC1 | |
| SCHEMBL18934437 | 0.78 | HTR4 (0.41) | BAZ2BPLK1BRD4 | |
| SCHEMBL24752653 | 0.77 | BAZ2B (0.37) | BAZ2BPLK1KAT2BGAAPARP1 | |
| SCHEMBL8294478 | 0.76 | KDM4E (0.47) | BAZ2BPLK1KAT2BNPC1KDM4E | |
| SCHEMBL7391414 | 0.74 | RXRA (0.39) | MAOAMAOBKDM4EALDH1A1LMNA | |
| SCHEMBL6127893 | 0.73 | MAOA (0.47) | MAOAMAOBALDH1A1 | |
| SCHEMBL7980334 | 0.73 | PARP1 (0.66) | BAZ2BPLK1KAT2BRAB9AGAA | |
| SCHEMBL20127247 | 0.72 | MAOA (0.41) | MAOAMAOBPOLBRAB9APARP1 | |
| SCHEMBL29208186 | 0.72 | KDM4E (0.42) | BAZ2BPLK1KAT2BPARP1BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023034812-A1 | COMPOUNDS AND METHODS FOR MODULATING SPLICING | REMIX THERAPEUTICS INC. (US) | 2023-03-09 | — | — | WO | disclosed |