Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | NCF1 | P14598 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 5/20 | 0.33 |
| ▸ | HTR2C | P28335 | 5/20 | 0.33 |
| ▸ | PYGL | P06737 | 1/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | RAD52 | P43351 | 1/20 | 0.31 |
| ▸ | CASP7 | P55210 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25105750 | 1.00 | JAK2 (0.38) | JAK2SIGMAR1NCF1MEN1KMT2A | |
| SCHEMBL25105756 | 1.00 | JAK2 (0.38) | JAK2SIGMAR1NCF1MEN1KMT2A | |
| SCHEMBL8435327 | 0.93 | NCF1 (0.39) | JAK2NCF1MEN1KMT2AHTR2A | |
| SCHEMBL13939986 | 0.93 | NCF1 (0.34) | JAK2NCF1MEN1KMT2AHTR2A | |
| SCHEMBL13874489 | 0.86 | MEN1 (0.38) | NCF1MEN1KMT2AHTR2AHTR2C | |
| SCHEMBL13200784 | 0.84 | ADH1C (0.38) | NCF1MEN1KMT2AHTR2AHTR2C | |
| SCHEMBL14302735 | 0.84 | NCF1 (0.33) | JAK2NCF1 | |
| SCHEMBL18136209 | 0.83 | SIGMAR1 (0.31) | SIGMAR1 | |
| SCHEMBL8442130 | 0.83 | HTR2A (0.41) | NCF1MEN1KMT2AHTR2AHTR2C | |
| SCHEMBL8257091 | 0.82 | HRH3 (0.32) | HTR2AHTR2CMCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023034836-A1 | COMPOUNDS AND METHODS FOR MODULATING SPLICING | REMIX THERAPEUTICS INC. (US) | 2023-03-09 | — | — | WO | disclosed |