SCHEMBL25108

SCHEMBL25108

[c]1cccc2c1ccc1ccccc12

nearest known ligand 0.55

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.55
HSD17B10 Q99714 4/20 0.55
CYP2A6 P11509 4/20 0.55
TSHR P16473 2/20 0.55
TDP1 Q9NUW8 1/20 0.55
HPRT1 P00492 3/20 0.50
HIF1A Q16665 1/20 0.46
CYP1B1 Q16678 1/20 0.46
PAX8 Q06710 1/20 0.41
CYP1A2 P05177 3/20 0.39
HPGD P15428 2/20 0.39
CYP3A4 P08684 1/20 0.38
PTPN22 Q9Y2R2 1/20 0.37
THRB P10828 1/20 0.36
KDM4E B2RXH2 1/20 0.35
GAA P10253 1/20 0.35
MAPT P10636 1/20 0.35
TAAR1 Q96RJ0 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27732677 0.98 ALDH1A1 (0.52) ALDH1A1HSD17B10CYP2A6TSHRTDP1
Methane SCHEMBL28133192 0.98 ALDH1A1 (0.52) ALDH1A1HSD17B10CYP2A6TSHRTDP1
Hydroxyl Radical SCHEMBL28094644 0.98 ALDH1A1 (0.52) ALDH1A1HSD17B10CYP2A6TSHRTDP1
SCHEMBL534974 0.96 HPRT1 (0.58) ALDH1A1HSD17B10CYP2A6TSHRTDP1
SCHEMBL18221904 0.92 ALDH1A1 (0.61) ALDH1A1HSD17B10CYP2A6TSHRTDP1
SCHEMBL28140263 0.89 ALDH1A1 (0.43) ALDH1A1HSD17B10CYP2A6TSHRTDP1
Pyridine SCHEMBL28157963 0.87 ALDH1A1 (0.41) ALDH1A1HSD17B10CYP2A6TSHRTDP1
SCHEMBL28130707 0.87 HPRT1 (0.48) ALDH1A1HSD17B10CYP2A6TSHRTDP1
SCHEMBL28294913 0.87 ALDH1A1 (0.41) ALDH1A1HSD17B10CYP2A6TSHRTDP1
Triphenylene SCHEMBL28342090 0.87 HPRT1 (0.43) ALDH1A1HSD17B10CYP2A6TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 7509 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12041848-B2 Heterocyclic compound and organic light emitting element comprising same LG CHEM, LTD. (KR) 2024-07-16 US claimed
US-12018122-B2 Method for producing silane-modified polymers MERZ+BENTELI AG (CH) 2024-06-25 US claimed
EP-3281238-B1 SEMICONDUCTING MATERIAL COMPRISING A PHOSPHINE OXIDE MATRIX AND METAL SALT NOVALED GMBH (DE) 2024-04-24 EP claimed
EP-3378853-B1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME LG CHEMICAL LTD (KR) 2024-04-17 EP claimed
US-20240074230-A1 MATERIALS FOR FORMING A NUCLEATION-INHIBITING COATING AND DEVICES INCORPORATING SAME OTI LUMIONICS INC. (CA) 2024-02-29 US claimed
CN-115557879-B Compound and organic electronic device comprising same 株式会社LG化学 2024-02-20 CN claimed
US-11877509-B2 Organic light-emitting element LG CHEM, LTD. 2024-01-16 US claimed
CN-117304374-A Olefin polymerization metallocene catalyst composition, and preparation and application thereof 中国石油天然气股份有限公司 2023-12-29 CN claimed
WO-2023246009-A1 OLEFIN POLYMERIZATION METALLOCENE CATALYST COMPOSITION, PREPARATION THEREOF AND USE THEREOF 中国石油天然气股份有限公司 2023-12-28 WO claimed
CN-117285668-A Ethylene-propylene copolymer catalyst composition and preparation and application thereof 中国石油天然气股份有限公司 2023-12-26 CN claimed
US-5847227-A Method for producing aryl alkyl hydroperoxides MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1998-12-08 US claimed
WO-1998045336-A2 METHOD FOR PREPARING (CO)POLYMERS BY METAL-FREE ANIONIC POLYMERIZATION BASF AKTIENGESELLSCHAFT (DE) 1998-10-15 WO claimed
WO-1998023616-A1 BIARYL-PYRIDOQUINAZOLINONE DERIVATIVES AS ANTI-CANCER AGENTS AMERICAN CYANAMID COMPANY (US) 1998-06-04 WO claimed
EP-0729938-A2 A method for producing aryl alkyl hydroperoxides MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1996-09-04 EP claimed
US-5464926-A Synthesis and polymerization of oligomeric multiple aromatic ether-containing phthalonitriles THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 1995-11-07 US claimed
US-5352760-A Polymerization of oligomeric multiple aromatic ether-containing phthalonitriles THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 1994-10-04 US claimed
US-5338637-A High in photosensitivity, low in residual potential and high in photoreception repsonse speed KONICA CORPORATION (JP) 1994-08-16 US claimed
US-5312707-A Compositions for images RICOH COMPANY, LTD. (JP) 1994-05-17 US claimed
US-4937164-A AS PHOTOGENERATOR WITH CHARGE TRANSPORT LAYER XEROX CORPORATION (US) 1990-06-26 US claimed
US-4882254-A Photoconductive imaging members with mixtures of photogenerator pigment compositions XEROX CORPORATION (US) 1989-11-21 US claimed