SCHEMBL28294913

SCHEMBL28294913

[c]1c2ccccc2cc2ccccc12.[c]1cccc2c1ccc1ccccc12

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.41
HSD17B10 Q99714 3/20 0.41
CYP2A6 P11509 2/20 0.41
TSHR P16473 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
CYP1B1 Q16678 2/20 0.41
HIF1A Q16665 1/20 0.41
CYP1A2 P05177 3/20 0.40
HPGD P15428 2/20 0.40
HPRT1 P00492 3/20 0.39
ERBB2 P04626 1/20 0.34
FYN P06241 1/20 0.34
MAOA P21397 1/20 0.34
ACHE P22303 1/20 0.34
AHR P35869 1/20 0.34
PAX8 Q06710 1/20 0.33
HTR2A P28223 1/20 0.32
NQO2 P16083 1/20 0.31
CYP1A1 P04798 1/20 0.31
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25108 0.87 ALDH1A1 (0.55) ALDH1A1HSD17B10CYP2A6TSHRTDP1
SCHEMBL11674210 0.85 CYP2A6 (0.31) ALDH1A1HSD17B10CYP2A6TDP1HIF1A
Methane SCHEMBL28133192 0.85 ALDH1A1 (0.52) ALDH1A1HSD17B10CYP2A6TSHRTDP1
Hydroxyl Radical SCHEMBL28094644 0.85 ALDH1A1 (0.52) ALDH1A1HSD17B10CYP2A6TSHRTDP1
SCHEMBL27732677 0.85 ALDH1A1 (0.52) ALDH1A1HSD17B10CYP2A6TSHRTDP1
SCHEMBL18221904 0.84 ALDH1A1 (0.61) ALDH1A1HSD17B10CYP2A6TSHRTDP1
SCHEMBL534974 0.83 HPRT1 (0.58) ALDH1A1HSD17B10CYP2A6TSHRTDP1
Triphenylene SCHEMBL29287879 0.81 ALDH1A1 (0.35) ALDH1A1HSD17B10TSHRHIF1ACYP1A2
SCHEMBL1168422 0.80 ALDH1A1 (0.50) ALDH1A1HSD17B10CYP2A6TSHRTDP1
SCHEMBL1901239 0.80 ALDH1A1 (0.56) ALDH1A1HSD17B10CYP2A6TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109804042-A Luminaire and electronic device including luminaire 陶氏环球技术有限责任公司 2019-05-24 CN disclosed