Methane

Methane

SCHEMBL28133192

C.[c]1cccc2c1ccc1ccccc12

nearest known ligand 0.52

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Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.52
HSD17B10 Q99714 4/20 0.52
CYP2A6 P11509 4/20 0.52
TSHR P16473 2/20 0.52
TDP1 Q9NUW8 1/20 0.52
HPRT1 P00492 3/20 0.48
HIF1A Q16665 1/20 0.44
CYP1B1 Q16678 1/20 0.44
PAX8 Q06710 1/20 0.40
CYP1A2 P05177 3/20 0.38
HPGD P15428 2/20 0.38
CYP3A4 P08684 1/20 0.36
PTPN22 Q9Y2R2 1/20 0.35
THRB P10828 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25108 0.98 ALDH1A1 (0.55) ALDH1A1HSD17B10CYP2A6TSHRTDP1
SCHEMBL27732677 0.96 ALDH1A1 (0.52) ALDH1A1HSD17B10CYP2A6TSHRTDP1
Hydroxyl Radical SCHEMBL28094644 0.96 ALDH1A1 (0.52) ALDH1A1HSD17B10CYP2A6TSHRTDP1
SCHEMBL534974 0.94 HPRT1 (0.58) ALDH1A1HSD17B10CYP2A6TSHRTDP1
SCHEMBL18221904 0.90 ALDH1A1 (0.61) ALDH1A1HSD17B10CYP2A6TSHRTDP1
SCHEMBL28140263 0.87 ALDH1A1 (0.43) ALDH1A1HSD17B10CYP2A6TSHRTDP1
Triphenylene SCHEMBL28342090 0.85 HPRT1 (0.43) ALDH1A1HSD17B10CYP2A6TSHRTDP1
SCHEMBL28130707 0.85 HPRT1 (0.48) ALDH1A1HSD17B10CYP2A6TSHRTDP1
SCHEMBL28294913 0.85 ALDH1A1 (0.41) ALDH1A1HSD17B10CYP2A6TSHRTDP1
Pyridine SCHEMBL28157963 0.85 ALDH1A1 (0.41) ALDH1A1HSD17B10CYP2A6TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106458807-B New compound and spice composition containing it 高砂香料工业株式会社 2019-09-24 CN disclosed
CN-106458807-A Novel compound and fragrance composition containing same 高砂香料工业株式会社 2017-02-22 CN disclosed