Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.34 |
| ▸ | HTR1A | P08908 | 2/20 | 0.34 |
| ▸ | NR2E1 | Q9Y466 | 4/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.33 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.32 |
| ▸ | HTR2B | P41595 | 3/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.32 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.32 |
| ▸ | HTR2A | P28223 | 2/20 | 0.32 |
| ▸ | HTR2C | P28335 | 2/20 | 0.32 |
| ▸ | SCN1A | P35498 | 2/20 | 0.32 |
| ▸ | HTR6 | P50406 | 2/20 | 0.32 |
| ▸ | SLC10A1 | Q14973 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2510951 | 0.92 | ALDH1A1 (0.40) | ALDH1A1KDM4EHPGDADRB2HTR1A | |
| SCHEMBL12416580 | 0.81 | NR2E1 (0.45) | ALDH1A1KDM4EHPGDADRB2HTR1A | |
| SCHEMBL12446624 | 0.80 | KDM4E (0.46) | ALDH1A1KDM4EHPGDPTGS2NCEH1 | |
| SCHEMBL13380525 | 0.77 | LMNA (0.43) | ALDH1A1KDM4EADRB2HTR1ACYP1A2 | |
| SCHEMBL13380544 | 0.77 | NCEH1 (0.49) | ALDH1A1KDM4EHPGDNCEH1SMN1; SMN2 | |
| SCHEMBL19712930 | 0.77 | NCEH1 (0.43) | ALDH1A1KDM4EHPGDNCEH1DRD3 | |
| SCHEMBL29549156 | 0.77 | NCEH1 (0.43) | ALDH1A1KDM4EHPGDNCEH1DRD3 | |
| SCHEMBL12446625 | 0.74 | LMNA (0.40) | ALDH1A1KDM4EADRB2HTR1ACYP1A2 | |
| SCHEMBL17034129 | 0.74 | ADRB2 (0.45) | KDM4EADRB2HTR1ACYP1A2ADRB1 | |
| SCHEMBL17034340 | 0.74 | ADRB2 (0.45) | ALDH1A1KDM4EADRB2HTR1ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2376573-A2 | DENTAL COMPOSITION COMPRISING BIPHENYL DI(METH)ACRYLATE MONOMER COMPRISING URETHANE MOIETIES | 3M Innovative Properties Company (US) | 2011-10-19 | — | — | EP | disclosed |